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Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Dicentrine reduced heart disease risk factors in rats, T-588 protected mice brains without side effects, Provir blocked herpes virus and lessened mouse symptoms, and LY191704 could treat hair loss and prostate issues.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Testosterone helps human pancreatic cells increase insulin release.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Tadalafil is effective for treating urinary symptoms in men with BPH.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.

Finasteride effectively reduces hair loss by decreasing androgen levels.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Ageratum Conyzoides, when taken orally, can effectively reduce hair loss and improve hair growth.