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Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.

Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.

Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

Macrophage iron release is crucial for hair growth and wound healing.

JAK inhibitors show promise in effectively treating hair loss from alopecia areata.

IL-3 worsens lupus nephritis and blocking it improves kidney health.

Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.

TLR4 is important in aging-related diseases and could be a new treatment target.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

DHT inhibition may increase spinal bone growth in ankylosing spondylitis.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.

Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.

Non-drug therapies show promise for hair regrowth but need more research.

Geriatric Julia Creek dunnarts often suffer from reproductive and skin diseases, impacting conservation efforts.

Canine pemphigus foliaceus involves significant immune activity and shares similarities with human pemphigus.

Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

No single ideal JAK inhibitor for alopecia areata has been determined; JAK3 inhibitors may be promising with fewer side effects.

Softer hydrogels help wounds heal better with less scarring.