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Hydroxyl radicals cause hair follicle cell death during chemotherapy by reducing Bcl-2 protein levels.

Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Proxalutamide helps COVID-19 patients get rid of the virus faster and recover quicker.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Tiny particles from brain cells help hair grow by targeting a specific hair growth pathway.

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

Cow placenta extract may help hair grow by increasing a growth factor but is less effective than minoxidil.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Silencing certain circadian clock genes increases skin pigmentation.

TLR4 is important in aging-related diseases and could be a new treatment target.

The skin is a large organ that plays a role in the immune system.

Alopecia areata patients have varied cancer risks, with some cancers being lower and others higher.

Four specific genes are linked to keloid formation and could be potential treatment targets.

Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.

UV exposure causes hair thinning, graying, and changes in hair growth cycles in mice.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Intermediate filaments are crucial for cell differentiation and stem cell function.

Hair dye ingredient PPD causes cell death and aging in human hair cells by altering microRNA levels.

Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.

Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Increasing EGR1 levels makes hair root cells grow faster.

Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.

Our microbiome may affect the development of the hair loss condition Alopecia Areata, but more research is needed to understand this relationship.