research Non-Invasive Human Skin Transcriptome Analysis Using mRNA in Skin Surface Lipids
A new non-invasive method can analyze skin mRNA to understand skin diseases better.
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research Single-Cell Transcriptomics Defines Keratinocyte Differentiation in Avian Scutate Scales
The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
research Non-Invasive Human Skin Transcriptome Analysis Using mRNA in Skin Surface Lipids
The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.
research Human Induced Pluripotent Stem Cell-Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo
Human stem cells can help form hair follicles in mice.
research Applications of Exosomal miRNAs from Mesenchymal Stem Cells as Skin Boosters
Exosomal miRNAs from stem cells can help improve skin health and delay aging.
research Mitochondria Dysfunction and Inflammation in Traumatic Brain Injury: Androgens to the Battlefront
Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.
research Pili Torti: A Feature of Numerous Congenital and Acquired Conditions
Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.
research Transcriptome Profiling and Differential Gene Expression in Canine Microdissected Anagen and Telogen Hair Follicles and Interfollicular Epidermis
Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.
research In Vitro Hair Growth-Promoting Effects of Araliadiol via the p38/PPAR-γ Signaling Pathway in Human Hair Follicle Stem Cells and Dermal Papilla Cells
Araliadiol may promote hair growth like minoxidil without being toxic.
research Hair Growth-Promoting Effect of the Coffee Bean Residue Extract on Hair Follicle Dermal Papilla Cells via the Activation of Autophagy
Coffee bean residue extract helps hair growth by activating cell processes.
research Exosomal MicroRNA-Based Therapies for Skin Diseases
miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
research Bioengineered Skin Organoids: From Development to Applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
research Grp1-Associated Scaffold Protein Regulates Skin Homeostasis After Ultraviolet Irradiation
Grasp protein helps maintain skin health after UVB exposure.
research EGFR Controls Hair Shaft Differentiation in a p53-Independent Manner
EGFR helps control how hair grows and forms without needing p53 protein.
research Septin4 Promotes Cell Death in Human Colon Cancer Cells by Interacting with BAX
Septin4 helps kill colon cancer cells by working with the protein BAX.
research De Novo Assembly and Annotation of Asiatic Lion (Panthera Leo Persica) Genome
The Asiatic lion has very low genetic diversity and unique genetic traits, highlighting the need for its conservation.
research Apoptosis and Cutaneous Biology
Apoptosis is crucial for healthy skin and treating skin diseases.
research Cashmere Growth Control in Liaoning Cashmere Goat by Ovarian Carcinoma Immunoreactive Antigen-Like Protein 2 and Decorin Genes
OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.
research Possible Therapeutic Effects of Ozone Mixture on Hypoxia in Tumor Development
Ozone therapy might improve cancer treatment and reduce its side effects.
research P53 Involvement in the Control of Murine Hair Follicle Regression
The p53 protein helps control hair follicle shrinking by promoting cell death in mice.
research Isolation and Characterization of Recombinant Murine Wnt3a
Scientists successfully purified a protein called Wnt3a, which is involved in processes like hair growth, but the overall yield was low, suggesting more work is needed to improve this.
research Epimorphic Regeneration in Mice Is p53-Independent
Mice can regenerate ear tissue without the p53 protein.
research FLCN, A Novel Autophagy Component, Interacts With GABARAP And Is Regulated By ULK1 Phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Regeneration After Facial Nerve Injury
Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
research Adrenal Cortex Tumors and Hyperplasias
Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.
research The Role of Histone Demethylases in Disease
Histone demethylases play a key role in the development of many diseases and may be targets for treatment.
research Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications
Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
research Role of Annexin A2 Isoform 2 on the Aggregative Growth of Dermal Papillae Cells
Annexin A2 isoform 2 helps dermal papillae cells grow, affecting hair growth.
research ST14 Interacts With TMEFF1 and Is a Predictor of Poor Prognosis in Ovarian Cancer
High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.
research Niacinamide Down-Regulates the Expression of DKK-1 and Protects Cells from Oxidative Stress in Cultured Human Dermal Papilla Cells
Vitamin B3 may help prevent hair loss and promote hair growth by protecting scalp cells from stress and reducing hair growth-blocking proteins.