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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Polymeric nanoparticles show promise for treating skin diseases.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

New effective scar treatments are urgently needed due to the current options' limited success.

Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

Fat cells in the skin help start healing and form important repair cells after injury.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.