January 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a reliable RP-HPLC method for the simultaneous estimation of Spironolactone and Hydrochlorothiazide, which was validated as accurate, precise, and robust for pharmaceutical applications.
5 citations
,
September 2015 in “Journal of The American Academy of Dermatology” This letter highlights that the effectiveness of skin self-photography for melanoma detection has not been evaluated, although it could be a cost-effective option for patients without access to professional skin photography.
11 citations
,
December 2002 in “Controlled Clinical Trials” This study suggests that simple absolute threshold monitoring rules for compliance using the biomarker DHT perform similarly to more complex methods in the Prostate Cancer Prevention Trial.
26 citations
,
August 2018 in “Journal of Investigative Dermatology” This study found that TRPV3 activation in human sebocytes inhibits lipid synthesis and triggers proinflammatory cytokine expression, suggesting a role in the pathogenesis of dry skin-associated inflammatory dermatoses.
February 2016 in “PubMed” This review discusses testosterone replacement therapy, highlighting that most studies report no increased myocardial infarction risk when the therapy is properly administered with controlled hormone levels; it calls for careful consideration despite insurance coverage challenges.
2 citations
,
March 2014 in “European Journal of Chemistry” This study developed and validated a liquid chromatography-mass spectrometry method for accurately identifying and quantifying tamsulosin and finasteride in pharmaceutical forms, showing its effectiveness for quality control.
8 citations
,
April 2022 in “International Journal of Environmental Research and Public Health” This study found that pediatric epilepsy patients on polytherapy experienced more adverse drug reactions compared to those on monotherapy, despite improved seizure control with polytherapy.
22 citations
,
May 2011 in “European Journal of Cancer” This phase I study determined that a combination of oral SU-014813 and docetaxel is a feasible treatment with a manageable safety profile and potential anti-tumor activity, particularly noted in melanoma and GIST patients.
175 citations
,
December 1980 in “Archives of Dermatology” In this study, researchers examined two new cases of trichothiodystrophy and observed that the condition is linked to decreased synthesis of high-sulfur matrix proteins in hair.
1 citations
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January 2010 in “Via Medica Journals” This review discusses key aspects and challenges of thyroid ultrasound interpretation but reports no new clinical findings, noting the necessity of experience and theoretical knowledge in this field.
5 citations
,
January 2011 in “Der Pharmacia Lettre” This study validated a precise and sensitive reverse phase high performance liquid chromatographic method for determining Finasteride and Tamsulosin concentrations in bulk and tablet forms, with satisfactory accuracy and reproducibility.
8 citations
,
September 2022 in “Human genomics” This study identified a coexpression network and key genes associated with thyroid eye disease, potentially aiding in its treatment and diagnosis.
2 citations
,
March 2010 in “Acta Biochimica Polonica” This study observed that conjugates of the anticancer drug raltitrexed with dextran and albumin were more cytotoxic than the free drug at high concentrations, altering cell cycle effects.
October 2022 in “Linköping University medical dissertations” This abstract only provides a list of abbreviations and does not report any new research findings or results.
62 citations
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December 1941 in “Experimental biology and medicine” In this study, phenylthiocarbamide intake was associated with hair graying in rats, while switching to tap water led some rats to regain their original fur color, suggesting dietary factors influence pigmentation.
3 citations
,
November 1998 in “PubMed” This study found that finasteride significantly inhibits the metabolism of tirilazad to its active metabolites without greatly affecting tirilazad's overall clearance.
January 2020 in “SCIENCE, ENGINEERING AND TECHNOLOGY: GLOBAL TRENDS, PROBLEMS AND SOLUTIONS” This conference proceedings compilation from Prague covers global trends, problems, and solutions in science, engineering, and technology, but reports no new clinical results.
40 citations
,
October 2009 in “Journal of Biomedical Nanotechnology” This review discusses pyrene excimer nucleic acid probes for detecting biomolecules and protein-DNA interactions and reports no new experimental findings.
3 citations
,
December 2018 in “Meta Gene” This study applied a prediction model based on five SNPs to Russian males with male pattern hair loss, finding a significant association between the AR genomic region and high dihydrotestosterone levels in these patients.
December 2009 in “Saengmyeong gwahag hoeji/Saengmyeong gwahak hoeji” This study observed that thymosin beta 4 and VEGF have similar expression patterns in various human tissues, suggesting a role in angiogenesis and organ function.
June 2023 in “British Journal of Dermatology” In this case report, researchers described a female child with total alopecia due to a mutation in the SNRPE gene, emphasizing the need for updated genetic testing as knowledge advances to avoid diagnostic delays in hereditary nonsyndromic hypotrichosis.
February 2016 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” This study reports a novel mutation in the TP63 gene associated with T and B cell lymphopenia in an EEC patient, suggesting that EEC diagnosis should include TREC assay and evaluation for immunodeficiency.
21 citations
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January 2008 in “Talanta” New, cheaper method measures finasteride in tablets accurately and quickly.
59 citations
,
September 2007 in “Biochemical and Biophysical Research Communications” This study found that a gain-of-function mutation in the TRPV3 channel leads to altered hair development in DS-Nh mice by affecting the anagen and telogen phases, highlighting TRPV3's role in hair growth regulation.
3 citations
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January 2019 in “Česká a slovenská farmacie” This review discusses various types of microneedles and their potential to expand the range of drugs delivered via the skin, but reports no new clinical results.
34 citations
,
January 2004 in “Genomics” In this study, researchers identified a cluster of hair-specific keratin-associated protein genes within the 21q22.3 region, revealing a novel transcription mechanism involving TSPEAR/C21orf29 that may bypass typical transcriptional termination sites.
7 citations
,
April 2015 in “Journal of biological chemistry/The Journal of biological chemistry” This study reports the development of a novel protocol to purify human TRPV3 ion channels, revealing functional properties and differences in ligand interactions, enabling further structural and functional research.
22 citations
,
November 2002 in “Clinical journal of oncology nursing” This article discusses arsenic trioxide as a treatment for refractory or relapsed acute promyelocytic leukemia, noting its effectiveness and manageable side effects.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study discovered that the gene Tfap2b identifies a melanocyte stem cell population in zebrafish, essential for regenerating melanocytes with multi-fate potential into adult pigment cells.
January 2008 in “Vestnik Tomskogo gosudarstvennogo universiteta Filologiya” This study found that overexpressing thymosin beta-4 in transgenic cashmere goats could potentially increase cashmere yield by boosting the number of secondary hair follicles.