TLDR The method accurately measures Finasteride and Tamsulosin in tablets without interference.
A reverse phase high performance liquid chromatographic (RP HPLC) method was developed and validated for determining Finasteride and Tamsulosin in bulk and tablet forms. The method demonstrated that tablet excipients did not interfere with drug quantification. The HPLC used a Shimadzu system with a hypersil ODS C18 column and a mobile phase of acetonitrile and KH2PO4 buffer. Detection occurred at 240 nm, with linearity ranges of 125-625 mg/ml for Finasteride and 10-50 mg/ml for Tamsulosin. The method showed adequate sensitivity, reproducibility, and specificity, with satisfactory accuracy and precision, achieving recovery rates of 100.76% for Finasteride and 99.06% for Tamsulosin.
February 2021 in “European Chemical Bulletin” A reliable method was developed to measure Minoxidil and Finasteride accurately in medicines.
January 2015 in “INDONESIAN JOURNAL OF PHARMACY” A reliable method was developed to measure Tamsulosin and Finasteride in tablets accurately.
5 citations
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February 2014 in “Journal of Liquid Chromatography & Related Technologies” Method accurately measures finasteride and tamsulosin in combined drug form.
1 citations
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January 2012 in “Analytical chemistry, an Indian journal” A reliable method was developed to accurately measure tamsulosin hydrochloride and finasteride in tablets.
A new method accurately measures Finasteride and Tamsulosin in tablets.
14 citations
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January 2011 in “Journal of analytical & bioanalytical techniques” Created accurate method to measure tamsulosin hydrochloride and finasteride in tablets.
26 citations
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June 2010 in “Acta Pharmaceutica” Methods accurately measure tamsulosin hydrochloride and finasteride in combined dosages.
1 citations
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December 2009 in “Asian Journal of Research in Chemistry” The methods accurately measure Finasteride and Tamsulosin in tablets.
Three reliable methods were developed to measure Finasteride and Tamsulosin Hydrochloride in medicines.