RP HPLC Method for the Determination of Finasteride and Tamsulosin in Bulk and Pharmaceutical Formulations

January 2011 in “ Der Pharmacia Lettre ”

Manish Kumar Thimmaraju, Venkat K. Rao, Srikanth Gurrala

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research RP-HPLC Method for Simultaneous Estimation of Finasteride and Tamsulosin in Tablet Formulations

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The study aimed to develop a simple and precise RP-HPLC method for the simultaneous estimation of Tamsulosin and Finasteride in bulk and tablet formulations. The method utilized a Spherisorb C-18 column with an isocratic flow and detection at 210 nm, using a mobile phase of methanol and phosphate buffer. It demonstrated a linear response for Tamsulosin and Finasteride within specific concentration ranges, with limits of detection and quantitation established for both drugs. The recovery rates were high, and the low %RSD values indicated good precision and stability. The method was concluded to be selective and potentially useful for estimating these drugs in combined dosage forms.

research Simultaneous Determination of Finasteride and Tamsulosin in Combined Dosage Form by Using RP-HPLC Method

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research RP-HPLC Assay Method for Simultaneous Estimation of Tamsulosin Hydrochloride and Finasteride in Pharmaceutical Dosage Form

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HPTLC Method Validation for Simultaneous Determination of Tamsulosin Hydrochloride and Finasteride in Bulk and Pharmaceutical Dosage Form

research HPTLC Method Validation for Simultaneous Determination of Tamsulosin Hydrochloride and Finasteride in Bulk and Pharmaceutical Dosage Form

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research Validated RP-HPLC and TLC Methods for Simultaneous Estimation of Tamsulosin Hydrochloride and Finasteride in Combined Dosage Forms

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research Spectrophotometric and Stability Indicating RP-HPLC-PDA Method for Simultaneous Determination of Finasteride and Tamsulosin in Combined Tablet Dosage Form

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research Simultaneous Estimation of Finateride and Tamsulosin Hydrochloride in Pharmaceutical Dosage forms by Uv Spectrophotometric, RP-HPLC and HPTLC Methods.

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