57 citations,
March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
55 citations,
October 2014 in “Development” Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.
50 citations,
May 2019 in “Drugs” Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
44 citations,
September 2014 in “Cell Death & Differentiation” Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.
39 citations,
August 2008 in “Growth hormone & IGF research” Raspberry ketone may help grow hair and improve skin elasticity.
38 citations,
June 2015 in “Expert Opinion on Therapeutic Targets” Blocking the prolactin receptor might help treat various diseases, but more research is needed.
30 citations,
April 2010 in “Cell Cycle” The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.
28 citations,
January 2018 in “Biochemical Society Transactions” Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.
28 citations,
March 2017 in “Endocrinology” Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.
25 citations,
May 2020 in “EMBO reports” Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
25 citations,
June 2018 in “Journal of The American Academy of Dermatology” Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.
25 citations,
July 2017 in “Archives of Dermatological Research” Herbal products might promote hair growth with fewer side effects, but more research is needed to confirm their safety and effectiveness.
24 citations,
January 2020 in “International Journal of Molecular Sciences” Some plants with flavonoids may help treat hair loss and promote hair growth.
17 citations,
December 2015 in “International Journal of Cosmetic Science” Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.
16 citations,
July 2021 in “Histopathology” New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
16 citations,
May 2019 in “Hormone and Metabolic Research” Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.
15 citations,
December 2017 in “Journal of Investigative Dermatology” No strong genetic link to other skin conditions was found, but some genetic factors may make people more likely to get seborrheic dermatitis.
14 citations,
April 2021 in “Biology” Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.
11 citations,
August 2020 in “Diabetes” Testosterone helps human pancreatic cells increase insulin release.
10 citations,
May 2018 in “Nutrition and Cancer” Certain spices may help prevent and treat skin cancer, but more human trials are needed.
9 citations,
January 2005 in “Experimental dermatology” Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
9 citations,
January 1997 in “Gynecological Endocrinology” The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
8 citations,
November 2020 in “Optics and Laser Technology” LED light therapy is effective for skin and hair treatments but requires careful use to minimize risks.
6 citations,
December 2013 in “Journal of Cutaneous Pathology” Certain immune cells are more common on the top of the head and might help predict or treat common hair loss.
5 citations,
October 2014 in “Journal of cosmetic and laser therapy” Combining physical dermabrasion with chemical peeling is more effective for skin treatment than chemical peeling alone.
4 citations,
October 2020 in “Toxicology Mechanisms and Methods” Hesperidin protects rat testicles from finasteride damage and improves sperm health.
4 citations,
September 2016 in “Molecular Medicine Reports” Specific genes influence hair and cashmere growth in Laiwu black goats.
4 citations,
September 2021 in “Frontiers in allergy” The conclusion is that understanding the complex relationship between allergies, autoimmunity, and psychological factors is key to treating skin disorders with itching.
3 citations,
September 2023 in “Frontiers in immunology” Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.
3 citations,
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The unique coat of lykoi cats is likely caused by new variants in the Hairless gene.