January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Exosomes and stem-cell therapies slightly outperform PRP in improving hair and skin, but more research is needed.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Exosomes and stem-cell therapies slightly outperform PRP in improving hair and skin, but more research is needed.
May 2026 in “Journal of the Egyptian Womenʼs Dermatologic Society” This review discusses microneedling radiofrequency in cosmetic dermatology, particularly for skin texture improvement and various conditions, and reports no new clinical results.
59 citations
,
September 2007 in “Biochemical and Biophysical Research Communications” This study found that a gain-of-function mutation in the TRPV3 channel leads to altered hair development in DS-Nh mice by affecting the anagen and telogen phases, highlighting TRPV3's role in hair growth regulation.
3 citations
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August 2023 in “Drug safety” This source reports that trastuzumab deruxtecan improves outcomes in HER2-positive and HER2-low metastatic breast cancer, emphasizing the need for careful adverse event monitoring, particularly for interstitial lung disease, and managing emetic risk to maximize benefits.
1 citations
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September 2025 in “Frontiers in Immunology” In this study, researchers using a Treg-specific HuR-deficient mouse model found that the RNA-binding protein HuR is crucial for stabilizing Foxp3 mRNA, affecting Treg function and immune regulation, with HuR disruption leading to impaired Foxp3 expression and potential autoimmune dysfunction.
7 citations
,
March 2021 in “IntechOpen eBooks” In this chapter, the authors provide a detailed overview of the fundamental science and operational principles of radiofrequency technologies, particularly in enhancing liposuction procedures through minimally-invasive techniques like RF-assisted lipolysis and fractional RF subdermal treatment.
83 citations
,
January 2001 in “American journal of clinical dermatology” This review discusses the clinical features of trichotillomania and the challenges in its diagnosis and treatment, reporting no new clinical findings while highlighting the need for specialized therapy and better therapeutic options.
This study observed that combining PRP and Tressfix Serum significantly improved hair regrowth and reduced microRNA expression linked to Chronic Telogen Effluvium compared to using either treatment alone.
36 citations
,
July 2017 in “Journal of controlled release” In this study, a new formulation of all-trans retinoic acid bound to polyvinyl alcohol showed reduced skin inflammation and sustained drug release for up to six days compared to free ATRA in vitro and in vivo.
3 citations
,
December 2014 in “Aesthetic dermatology” This book reviews the evolving use of radiofrequency in aesthetic medicine and its comparison with laser and surgical approaches, but it reports no new clinical results.
2 citations
,
November 2004 in “Blood” In this study, researchers reported that the Pinkie mutation in mice, affecting RXRa activity, leads to skewed Th1 development and suggests RXRa's role in Th2 differentiation, impacting immune responses.
42 citations
,
August 1995 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that RXR-alpha is strongly expressed in both normal and psoriatic human skin, suggesting it may play a role in the transition from proliferation to differentiation in epidermal keratinocytes.
110 citations
,
July 2017 in “Immunology” This review discusses the role of regulatory T cells in skin, including their impact on hair follicle regeneration, wound healing, and immune tolerance, without presenting new clinical findings.
18 citations
,
May 1988 in “Journal of The American Academy of Dermatology” In this study, itraconazole was reported to effectively alleviate clinical symptoms in patients with recalcitrant Trichophyton rubrum infections, though toenail infections often recurred, indicating the need for further research on long-term efficacy and safety.
24 citations
,
June 2020 in “Dermatologic Therapy” This review discusses recent advances in the pharmacological treatment of trichotillomania, highlighting potential benefits of glutamate-modulating agents, and reports no new clinical results.
September 2024 in “Quality in Sport” This study provides a comprehensive review of trichotillomania, focusing on its clinical symptoms, etiology, diagnostics, and treatment methods, while also addressing serious complications like trichobezoars and Rapunzel Syndrome.
56 citations
,
November 1993 in “Journal of The American Academy of Dermatology” Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.
111 citations
,
April 2000 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, physiological levels of free T3 significantly enhanced the survival of human hair follicles in vitro.
October 2024 in “Cosmetics” In this study, subthermal RF-CRET currents were found to alter key molecular mechanisms in dermal papilla cells, promoting proliferation and survival while enhancing markers associated with hair growth and maintenance, suggesting potential benefits for hair regeneration.
January 2020 in “International Journal of Trichology” This study reported that platelet-rich plasma injections led to only temporary improvement in vellus hair characteristics in temporal triangular alopecia, suggesting it may not be an effective long-term treatment.
November 2024 in “Actas Dermo-Sifiliográficas” This review outlines current treatment strategies for trichotillomania, noting that while cognitive-behavioral therapy is effective, N-acetylcysteine and memantine are also recommended due to their safety and efficacy, though evidence for other drugs like fluoxetine and naltrexone remains limited.
56 citations
,
January 2014 in “Journal of Investigative Dermatology” Olmsted syndrome can be inherited as an autosomal recessive trait due to a rare TRPV3 gene mutation.
3 citations
,
May 2025 in “Lasers in Surgery and Medicine” This study suggested that MRF may support skin regeneration and rejuvenation by promoting collagen synthesis and regulating factors involved in fibroblast activation and ECM remodeling, with preliminary findings indicating ADSCs might aid these processes.
15 citations
,
December 2020 in “The Journal of General Physiology” This study found that acid regulation of the TRPV3 channel can inhibit its function from outside the cell while facilitating it from inside, providing insights into skin barrier and disorder mechanisms related to tissue acidosis.
13 citations
,
March 2014 in “Journal of the American Medical Directors Association” This review discusses the characteristics, prevalence, and treatment challenges of trichotillomania and provides no new clinical findings.
November 2025 in “Journal of Investigative Dermatology” TEDAR is crucial for skin cell differentiation and barrier formation.
3 citations
,
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study suggests that platelet-rich plasma may improve pain and function in patients with partial-thickness rotator cuff tears and tendinopathy short-term, but the long-term benefits are unclear.
September 2017 in “Journal of Investigative Dermatology” LRIG1 protein affects hair growth by regulating skin receptors, leading to hair loss when overexpressed.
116 citations
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August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.