TLDR Clomipramine may significantly reduce hair-pulling in Trichotillomania, but more research is needed on treatments and early onset cases.
The 2001 document reviews Trichotillomania (TTM), an impulse control disorder causing individuals to pull out their hair, resulting in hair loss and psychological distress. Diagnosis is difficult due to patient denial or ignorance, and specialized scalp biopsies are often necessary. The most promising treatment mentioned is clomipramine, a tricyclic antidepressant, which in one study led to a 50% or greater reduction in symptoms for 12 out of 13 patients, although its long-term efficacy and tolerability are questionable. Other medications like SSRIs have shown mixed results. Habit reversal training is recommended as an effective behavioral therapy. TTM typically starts in late childhood or adolescence and is frequently comorbid with other psychiatric disorders. The document emphasizes the need for more tolerable medications, accessible therapy, and further research into early onset TTM and treatment efficacy.
44 citations,
November 1998 in “Australasian Journal of Dermatology” Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.
26 citations,
January 1993 in “Dermatology” Exclamation mark hairs are not exclusive to alopecia areata.
180 citations,
November 1991 in “American Journal of Psychiatry” Fluoxetine was not effective in treating hair-pulling disorder in the short term.
417 citations,
March 1991 in “American Journal of Psychiatry” Most adult chronic hair pullers are women who started in their early teens, often have other mental health issues, and may pull hair due to underlying psychiatric conditions.
January 2023 in “International Journal of Homoeopathic Sciences” Homoeopathic treatment may help restore hair in Alopecia Areata by balancing the immune system.
148 citations,
December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
May 2018 in “Journal of cosmetology & trichology” Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.
3 citations,
May 2010 in “Nursing Standard” Treatments for autoimmune hair loss have limited success and often relapse, and emotional support is crucial for those affected.