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GlossaryTricyclic Antidepressants

medications that treat depression by increasing certain brain neurotransmitters

Tricyclic Antidepressants (TCAs) are a class of medications primarily used to treat depression. They work by increasing the levels of certain neurotransmitters, such as serotonin and norepinephrine, in the brain, which helps improve mood. TCAs are also sometimes prescribed for chronic pain, anxiety disorders, and certain types of headaches. While effective, they can have significant side effects, including dry mouth, weight gain, and dizziness, which is why they are often not the first choice of treatment.

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research Adverse Cutaneous Reactions to Antidepressants

44 citations, January 2002 in “American Journal of Clinical Dermatology”

Skin reactions to antidepressants are common but usually not serious and can be treated.

research Squarticles as Nanoantidotes to Sequester Overdosed Antidepressants for Detoxification

9 citations, November 2017 in “International Journal of Nanomedicine”

Tiny particles called anionic squarticles can effectively remove a common antidepressant from the body after an overdose.

research Hair Loss With Antidepressants

8 citations, September 1993 in “Human psychopharmacology”

Some antidepressants can cause rare hair loss, which can significantly affect patients' well-being.

research Unconventional Side Effects of Antidepressants: Focus on Emotional Blunting

April 2017 in “European Psychiatry”

Some antidepressants can cause emotional numbness and other unusual side effects.

research Where It All Went Right: Secondary Uses of Drugs

1 citations, December 2014

Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.

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community Is hair thinning or loss associated with pain?

in Research/Science 6 upvotes 1 year ago

Hair thinning/loss associated with burning scalp pain. Finasteride helped relieve "DHT itch" for one person.

community 60-day progress with Minoxidil

in Progress Pictures 881 upvotes 10 months ago

A user shared a 60-day progress update on hair regrowth using only 5% Minoxidil foam once daily. Others suggested adding finasteride to address the underlying cause of hair loss and maintain long-term results.