Update on the Treatment of Trichotillomania

    November 2024 in “ Actas Dermo-Sifiliográficas ”
    L E Nina-Dominguez, Adrián Imbernón‐Moya, D Saceda-Corralo, Sérgio Vañó-Galván
    TLDR N-acetylcysteine and memantine are recommended as safe and effective treatments for trichotillomania.
    Trichotillomania (TTM) is an obsessive-compulsive disorder characterized by recurrent hair pulling, leading to hair loss or alopecia. Treating TTM is challenging and involves a combination of pharmacological and non-pharmacological methods. Cognitive-behavioral therapy is effective but not suitable for all patients. Alternative support tools like electronic devices, internet therapies, and microneedling are suggested. N-acetylcysteine and memantine are recommended as first-line treatments due to their safety and efficacy, with minimal adverse effects. Other drugs such as fluoxetine, clomipramine, olanzapine, and naltrexone show limited and variable efficacy. This review discusses current treatment options for managing TTM.
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