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Women with PCOS in Sicily show different levels of metabolic problems depending on their PCOS type, with obesity and abnormal lipid profiles being common.

High doses of certain vitamins can cause serious side effects and health risks.

Newer retinoid drugs are effective for skin conditions but have significant side effects.

PCOS is a common hormonal disorder in women that can be managed with lifestyle changes and various medications.

Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.

People with lichen planus are more likely to have dyslipidemia, especially higher triglyceride levels.

Menstrual abnormalities in PCOS women may not greatly affect their metabolic and hormonal profile.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Hormonal imbalances, not insulin resistance or dyslipidemia, may be more important in causing acne in women over 25.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

Patients with oral lichen planus or oral lichenoid reactions had worse cholesterol levels and a higher risk of obesity compared to healthy individuals.

A rabbit with sebaceous adenitis was effectively treated with ciclosporin and medium-chain triglycerides.

HSD3B1 gene variant and being overweight linked to hair loss in women with polycystic ovary syndrome.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.

Metformin and thiazolidinediones are similarly effective for PCOS, but metformin is often preferred due to fewer side effects.

Women with PCOS should have an oral glucose tolerance test for effective diabetes screening.

High doses of Lepidium sativum seed extract are toxic and should be used with caution.

Polycystic Ovary Syndrome (PCOS) can lead to diabetes, heart disease, cancer, and mental health problems.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.

Lower testosterone levels in men may be linked to a higher risk of severe coronary artery disease.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Women with PCOS in North China often have hirsutism and acne, with hirsutism linked to metabolic issues.

Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.