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    Glossary Diacylglycerol O-Acyltransferase 1

    enzyme that catalyzes the final step in triglyceride synthesis

    Diacylglycerol O-Acyltransferase 1 (DGAT1) is an enzyme that plays a crucial role in the body's ability to store fat. It catalyzes the final step in the synthesis of triglycerides, which are the main form of stored energy in fat cells. This enzyme is important for energy metabolism and has been studied for its potential links to obesity and metabolic disorders.

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    Research 10 of 216

    1. 696 MEK and BRAF inhibitors augment the production and accumulation of sebum in hamster sebocytes Journal of Investigative Dermatology · 2016
    2. The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5‐Independent Manner Experimental Dermatology · 2025
    3. The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters Journal of lipid research · 2005 · 258 citations
    4. The acyl-CoA binding protein is required for normal epidermal barrier function in mice Journal of Lipid Research · 2012 · 31 citations
    5. Unravelling the link between insulin resistance and androgen excess University of Birmingham Institutional Research Archive (University of Birmingham) · 2015
    6. Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways Journal of Cellular Biochemistry · 2005 · 24 citations
    7. Alopecia in a Viable Phospholipase C Delta 1 and Phospholipase C Delta 3 Double Mutant PloS one · 2012 · 8 citations
    8. Potential role and therapeutic interests of myo-inositol in metabolic diseases Biochimie · 2013 · 369 citations
    9. Syndromes of Severe Insulin Resistance (SSIRs) 2004
    10. Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update Journal of Dermatological Science · 2012 · 52 citations
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