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    Glossary Diacylglycerol O-Acyltransferase 1

    enzyme that catalyzes the final step in triglyceride synthesis

    Diacylglycerol O-Acyltransferase 1 (DGAT1) is an enzyme that plays a crucial role in the body's ability to store fat. It catalyzes the final step in the synthesis of triglycerides, which are the main form of stored energy in fat cells. This enzyme is important for energy metabolism and has been studied for its potential links to obesity and metabolic disorders.

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    Research 30 of 216

    1. 696 MEK and BRAF inhibitors augment the production and accumulation of sebum in hamster sebocytes Journal of Investigative Dermatology · 2016
    2. The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5‐Independent Manner Experimental Dermatology · 2025
    3. The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters Journal of lipid research · 2005 · 258 citations
    4. The acyl-CoA binding protein is required for normal epidermal barrier function in mice Journal of Lipid Research · 2012 · 31 citations
    5. Unravelling the link between insulin resistance and androgen excess University of Birmingham Institutional Research Archive (University of Birmingham) · 2015
    6. Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways Journal of Cellular Biochemistry · 2005 · 24 citations
    7. Alopecia in a Viable Phospholipase C Delta 1 and Phospholipase C Delta 3 Double Mutant PloS one · 2012 · 8 citations
    8. Potential role and therapeutic interests of myo-inositol in metabolic diseases Biochimie · 2013 · 369 citations
    9. Syndromes of Severe Insulin Resistance (SSIRs) 2004
    10. Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update Journal of Dermatological Science · 2012 · 52 citations
    11. Retinoid Metabolism Is Altered in Human and Mouse Cicatricial Alopecia Journal of Investigative Dermatology · 2012 · 22 citations
    12. Role of Stearoyl-CoA Desaturase-1 in Skin Integrity and Whole Body Energy Balance Journal of Biological Chemistry · 2013 · 67 citations
    13. Genetic ablation of myelin protein zero-like 3 in mice increases energy expenditure, improves glycemic control, and reduces hepatic lipid synthesis American Journal of Physiology-endocrinology and Metabolism · 2013 · 14 citations
    14. Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome European journal of endocrinology · 2009 · 200 citations
    15. Acne, the Skin Microbiome, and Antibiotic Treatment American journal of clinical dermatology · 2019 · 134 citations
    16. Inhibition of Rat 5<i>α</i>-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of<i>Quercus acutissima</i>Cortex Evidence-based Complementary and Alternative Medicine · 2015 · 37 citations
    17. An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities Frontiers in Cell and Developmental Biology · 2020 · 23 citations
    18. Low Humidity Alters Epidermal Gene Expression in vivo Clinical Cosmetic and Investigational Dermatology · 2026
    19. use of dermoscope to differentiate Pityrosporum folliculitis and Acne vulgaris 2023
    20. Dietary vitamin A regulates wingless-related MMTV integration site signaling to alter the hair cycle Experimental Biology and Medicine · 2014 · 18 citations
    21. Hair cycle control by leptin as a new anagen inducer Experimental Dermatology · 2013 · 41 citations
    22. Sebaceous Gland Atrophy in Psoriasis: An Explanation for Psoriatic Alopecia? Journal of Investigative Dermatology · 2016 · 69 citations
    23. Bhringraj (Eclipta Alba): A Thorough Review Of Its Therapeutic Benefits And Uses International Journal of Research Publication and Reviews · 2025
    24. Molecular interactions of natural and synthetic steroids in female hamsters’ flank organs Journal of Dermatological Science · 2012 · 1 citations
    25. A guide to studying human dermal adipocytes in situ Experimental Dermatology · 2018 · 21 citations
    26. Circadian clocks: from stem cells to tissue homeostasis and regeneration EMBO Reports · 2017 · 84 citations
    27. Rac-dependent signaling from keratinocytes promotes differentiation of intradermal white adipocytes bioRxiv (Cold Spring Harbor Laboratory) · 2018 · 1 citations
    28. Vitamin B-Complex and its Relationship with the Health of Vegetarian People Natural Resources for Human Health · 2023
    29. Dermal niche signaling and epidermal stem cells Advances in stem cells and their niches · 2019
    30. Coronavirus Infection and Cholesterol Metabolism Frontiers in Immunology · 2022 · 55 citations