December 2021 in “IP Indian journal of clinical and experimental dermatology” In this study, trichoscopy was identified as a useful non-invasive tool to aid in the diagnosis of female pattern hair loss, with peri pilar sign and hair diameter variability being common findings.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified intramembrane proteolysis as a key feature of Astrotactin2 maturation, providing insights into its role in planar cell polarity hair patterning.
34 citations
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June 1992 in “Journal of Cutaneous Pathology” In this case study, electron microscopy revealed that harlequin ichthyosis involves giant mitochondria in keratinocytes and abnormal lamellar granule development, which may contribute to pathogenesis through altered lipid metabolism.
7 citations
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July 2014 in “BMJ case reports” This article reviews the rare skin disorder ichthyosis with confetti, highlighting the potential for future therapies using revertant stem cells, and reports no new clinical results.
January 2016 in “Journal of Clinical Dermatology” This study found that trichoscopy is useful for diagnosing androgenetic alopecia and alopecia areata, and the severity of androgenetic alopecia can be assessed with this method.
8 citations
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November 2009 in “The Neurologist/The neurologist” This case report highlights a 21-year-old woman with seizures, mental retardation, spastic diplegia, and ichthyosis consistent with Sjogren-Larsson syndrome, and emphasizes the importance of differential diagnosis when additional symptoms are present.
17 citations
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January 2011 in “Indian journal of dermatology, venereology, and leprology” This paper describes a rare case of keratosis follicularis spinulosa decalvans in a nine-year-old girl, a condition typically more severe in males due to its X-linked inheritance.
15 citations
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January 2018 in “Advances in experimental medicine and biology” This review discusses recent advances in understanding the structural hierarchy of trichocyte keratins, including their heterodimeric structure and distinct conformations impacting hair growth, with no new experimental results reported.
8 citations
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March 2015 in “International Journal of Oncology” This study successfully established Tsc2-deficient embryonic stem cells from Eker rats and found these cells have distinct gene expression compared to non-mutant cells, which could help identify new therapeutic targets for TSC-related pathogenesis.
27 citations
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December 1999 in “American Journal of Dermatopathology” This case report presents a patient with necrobiosis lipoidica exhibiting transepithelial elimination of cholesterol crystals through hair follicles, a finding previously associated with necrobiotic xanthogranuloma.
16 citations
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June 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that DHHC13 is crucial for hair anchoring and skin barrier function, with its deficiency in Zdhhc13(skc4) mice leading to cyclic alopecia and skin abnormalities due to cornifelin deficiencies.
13 citations
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January 2002 in “Clinics in dermatology” This study found that AHCC supplementation significantly reduced alopecia severity in Ara-C treated rats and mitigated liver injury-related side effects in mice treated with 6-MP and MTX.
January 2018 in “International Journal of Medical Reviews and Case Reports” This case study reports that a 6-year-old girl with pediculosis capitis experienced scalp pruritus, pustules, crusting, excoriation, and cicatricial alopecia but showed a good clinical response to permethrin and antibiotics, with no lice detected afterward.
17 citations
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April 1997 in “American Journal of Dermatopathology” This report provides the first microscopic description of pachyonychia congenita-associated alopecia, identifying a combination of histological features that might be unique to this condition.
12 citations
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July 2004 in “Molecular genetics and genomics” This study identifies a new mutation in the Scd1 gene in a strain of Kunming mice, causing skin and hair defects with the mildest impact among similar mutations.
13 citations
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January 2011 in “International Journal of Trichology” CTA is often mistaken for AA but doesn't respond to steroids and may require hair transplantation.
30 citations
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May 2005 in “Pediatric dermatology” This report reviews familial cases of aplasia cutis of the scalp, noting large irregular defects at the vertex or anterior along the sagittal suture in six families.
89 citations
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December 2010 in “The Journal of Dermatology” This study describes characteristic trichoscopic features of various hair loss diseases and proposes an algorithmic method for diagnosing them, but reports no new clinical results.
January 2023 in “Indian dermatology online journal” This case report describes a novel NECTIN4 gene mutation linked to ED-syndactyly syndrome 1 in a young girl, contributing to the understanding of this rare ectodermal dysplasia.
13 citations
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December 2001 in “Journal of Investigative Dermatology” This study demonstrated that the tracheal xenotransplant procedure is an effective technique for assessing the invasiveness of epidermal keratinocytes and studying factors affecting hair follicle formation.
December 2024 in “Archiv Euromedica” This review highlights that diagnosing cicatricial alopecia, a hair loss condition linked to several autoimmune diseases, requires trichoscopy and histopathological examination to differentiate it from similar conditions, with early diagnosis being crucial for effective management.
January 2006 in “Dianzi xianwei xuebao” This study observed that ultrastructural changes like lamellar bodies and electron-dense granules in the stratum corneum may aid in the early diagnosis of Netherton syndrome.
March 2026 in “South Asian Research Journal of Medical Sciences” In this case study, a 7-year-old boy with kerion celsi experienced persistent inflammation even after microbiological clearance; dermoscopic-guided removal of hair and keratin debris improved his condition, suggesting a novel inflammatory mechanism involving granulomatous response to keratinous debris in tinea capitis.
June 2001 in “European Journal of Dermatology” This case study describes a 54-year-old woman with a rare pattern of asymmetrical hair loss resembling androgenetic alopecia, alongside sparse body hair and near absence of eyebrows and eyelashes, while other ectodermal features were normal.
39 citations
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July 2000 in “British Journal of Dermatology” This report on identical female twins with folliculitis decalvans suggests a possible genetic component to the disease, marking the first such case in twins.
7 citations
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November 2010 in “Genesis” Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.
11 citations
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July 2022 in “International Journal of Molecular Sciences” This study found that treating reconstructed human epidermis with beta-lipohydroxy salicylic acid increased tight junction remnants in the stratum corneum, potentially affecting skin cohesion and desquamation.
June 2022 in “IP Indian journal of clinical and experimental dermatology” This case report discusses a benign trichofolliculoma in a 40-year-old woman, confirmed through histopathological examination with no recurrence noted during a one-year follow-up period.
In this case study, a shih tzu dog developed comedones and epidermal cysts on the abdominal skin following laparotomy, potentially due to the implantation of epidermal fragments into the dermis during surgery.
April 2026 in “Research Square” In this study, trichoscopic examination revealed that variations in hair diameter were more common in certain types of alopecia affecting the frontal scalp, suggesting the importance of evaluating the entire scalp for accurate diagnoses, although limitations include a single center design and small sample size.