Autoimmune Cicatricial Alopecia and the Role of Trichoscopy in Its Diagnosis: A Literature Review

    December 2024 in “ Archiv Euromedica ”
    Honorata Derlatka, Łukasz Skowron, Katarzyna Mazur, Sandra Sierociuk
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    TLDR Trichoscopy is essential for diagnosing and treating autoimmune cicatricial alopecia early.
    Cicatricial alopecia is a complex condition leading to permanent hair loss and is often linked with diseases like lichen planopilaris, sarcoidosis, systemic lupus erythematosus, and scleroderma, each having distinct trichoscopic features crucial for diagnosis. Trichoscopy, a non-invasive diagnostic tool, is vital for differentiating these conditions and, along with scalp biopsy, confirms the diagnosis. The literature review highlights the role of trichoscopy in diagnosing autoimmune cicatricial alopecia, particularly lichen planopilaris, which is thought to result from a cytotoxic autoimmune response. Early diagnosis and aggressive treatment are critical for improving outcomes and preventing further health issues.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

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      by nkrata in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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      in Chat  33 upvotes 3 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

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      in Research/Science  100 upvotes 1 year ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  56 upvotes 11 months ago
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      in Chat  113 upvotes 1 year ago
      A user shared their success with oral finasteride and topical minoxidil for hair loss, recommending these treatments to others. They emphasized the importance of informing others about effective treatments rather than relying on supplements.

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