Autoimmune Cicatricial Alopecia and the Role of Trichoscopy in Its Diagnosis: A Literature Review

    December 2024 in “ Archiv Euromedica ”
    Honorata Derlatka, Łukasz Skowron, Katarzyna Mazur, Sandra Sierociuk
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    TLDR Trichoscopy is essential for diagnosing and treating autoimmune cicatricial alopecia early.
    Cicatricial alopecia is a complex condition leading to permanent hair loss and is often linked with diseases like lichen planopilaris, sarcoidosis, systemic lupus erythematosus, and scleroderma, each having distinct trichoscopic features crucial for diagnosis. Trichoscopy, a non-invasive diagnostic tool, is vital for differentiating these conditions and, along with scalp biopsy, confirms the diagnosis. The literature review highlights the role of trichoscopy in diagnosing autoimmune cicatricial alopecia, particularly lichen planopilaris, which is thought to result from a cytotoxic autoimmune response. Early diagnosis and aggressive treatment are critical for improving outcomes and preventing further health issues.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 7 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Losing Hair on Dutasteride? You might have LPP

      in Research/Science  96 upvotes 3 weeks ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  57 upvotes 1 week ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

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