Familial Nonmembranous Aplasia Cutis of the Scalp
May 2005
in “
Pediatric dermatology
”
Studysummary This report reviews familial cases of aplasia cutis of the scalp, noting large irregular defects at the vertex or anterior along the sagittal suture in six families. Our plain-language summary of this paper — not a Tressless recommendation.
The document reports on six families where multiple members exhibited familial nonmembranous aplasia cutis of the scalp, a condition characterized by large, irregular defects typically located over the vertex or anterior to the vertex along the sagittal suture. This condition, which can be sporadic, has also been observed to follow an autosomal dominant inheritance pattern. The study highlights that the defects observed in these families were of the nonmembranous variant, which is one of the two main clinical variants of aplasia cutis of the scalp, the other being oval-shaped membranous aplasia cutis. The document also reviews previous reports and clinical pictures of the condition, confirming the nonmembranous type as the more common presentation in familial cases.
