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    Glossary Autosomal Dominant Inheritance

    one mutated gene from either parent can cause a trait

    Autosomal Dominant Inheritance is a pattern of genetic transmission where only one copy of a mutated gene from either parent is sufficient to cause a particular trait or disorder. This means that if one parent carries the dominant gene, there is a 50% chance that their child will inherit the condition. This type of inheritance can be seen in conditions like certain forms of alopecia, where the presence of a single altered gene can lead to hair loss.

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    1. Familial hypotrichosis of the scalp. Autosomal dominant inheritance in four generations. Acta Dermato Venereologica · 1991 · 17 citations
    2. AUTOSOMAL DOMINANT INHERITANCE OF ALOPECIA CONGENITA WITH KERATOSIS PALMO-PLANTARIS Pediatric Research · 1977
    3. Cystatin M/E Variant Causes Autosomal Dominant Keratosis Follicularis Spinulosa Decalvans by Dysregulating Cathepsins L and V Frontiers in Genetics · 2021 · 6 citations
    4. The inheritance of common baldness: Two B or not two B ? Journal of the American Academy of Dermatology · 1984 · 203 citations
    5. Pitfalls of mapping a large Turkish consanguineous family with vertical monilethrix inheritance. PubMed · 2009 · 4 citations
    6. Germline Mutation in ATR in Autosomal- Dominant Oropharyngeal Cancer Syndrome The American Journal of Human Genetics · 2012 · 71 citations
    7. Loose Anagen Hair as a Cause of Hereditary Hair Loss in Children Archives of Dermatology · 1992 · 55 citations
    8. Congenital hypotrichosis due to short anagen British Journal of Dermatology · 2000 · 42 citations
    9. Atrichia With Papular Lesions Archives of Dermatology · 1986 · 32 citations
    10. Familial Nonmembranous Aplasia Cutis of the Scalp Pediatric dermatology · 2005 · 30 citations
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