TLDR The condition is likely inherited in an autosomal-dominant pattern.
The document reported a case of atrichia with papular lesions in an 11-year-old boy with common variable immunodeficiency, with similar findings in his father, suggesting an autosomal-dominant inheritance pattern. This rare form of ectodermal dysplasia involved the shedding of normal fetal hair within the first three months, sparing eyelashes, and the development of keratin-filled follicular cysts on the skin, particularly on the face, neck, scalp, and extremities, between ages 2 and 26. Teeth and nails remained normal, and the inheritance pattern was previously thought to be autosomal recessive.
189 citations
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May 1991 in “Medical Entomology and Zoology”
November 2019 in “Harper's Textbook of Pediatric Dermatology” Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.
139 citations
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September 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.
7 citations
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December 2008 in “Expert Review of Dermatology” The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.
2 citations
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January 2013 in “Elsevier eBooks” The document explains the genetic causes and characteristics of inherited hair disorders.
Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.
