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technique to create small wounds in skin to activate collagen production and hair growth
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5 / 9 resultslearn Pyrilutamide
highly targeted anti-androgen that might have minimal systemic effects
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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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research Biology and Genetics of Hair
The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
research A Recurrent Intragenic Deletion in the Desmoglein 4 Gene Underlies Localized Autosomal Recessive Hypotrichosis
A gene deletion in DSG4 causes sparse hair in some Pakistani families.
research Novel D323G Mutation of DSG4 Gene in a Girl with Localized Autosomal Recessive Hypotrichosis Clinically Overlapped with Monilethrix
A new DSG4 gene mutation causes hair defects in a young girl.
research The Lanceolate Hair Rat Phenotype Results from a Missense Mutation in a Calcium Coordinating Site of the Desmoglein 4 Gene
A gene mutation causes lanceolate hair in rats by disrupting hair shaft integrity.
research Desmoglein 4 Mutations Underlie Localized Autosomal Recessive Hypotrichosis in Humans, Mice, and Rats
Mutations in the DSG4 gene cause fragile, sparse hair in humans, mice, and rats.
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5 / 219 resultscommunity A systematic bro-science review of DHT, 5AR, neurosteroids, sexual health and 5AR inhibitors
Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.
community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering
Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.
community [Serious] Experience with grey-market KX-826 (Pyrilutamide)
The user experienced reduced hair loss using grey-market KX-826 alongside Minoxidil foam, achieving better results with Minoxidil liquid but restricted to foam due to an allergy. Initial side effects included shortness of breath, racing heart, and dizziness, which subsided after the first week.
community (Almost) 3 Year Hairline Update 33M: Minoxidil, Finasteride, Nizoral, and some Dermarolling
A user shared a nearly 3-year update on their hairline improvement using Minoxidil, Finasteride, Nizoral, and Dermarolling. Other users commented on the success and discussed their own experiences with similar treatments.
community Dr. Kyle Gillet on Dr. Andrew Huberman's podcast said dutasteride mesotherapy blocks DHT conversion only in the scalp and called it the most promising topical currently. What's the scoop?
Dr. Kyle Gillet mentioned on Dr. Andrew Huberman's podcast that dutasteride mesotherapy blocks DHT conversion only in the scalp and is the most promising topical treatment. Users discussed concerns about systemic absorption and the practicality of dutasteride injections.