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GlossaryLocalized Autosomal Recessive Hypotrichosis

genetic condition causing sparse or absent hair in specific areas

Localized Autosomal Recessive Hypotrichosis is a genetic condition characterized by sparse or absent hair in specific areas of the body. It is inherited in an autosomal recessive manner, meaning that an individual must inherit two copies of the mutated gene, one from each parent, to exhibit the condition.

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community It’s really unfortunate the CB-03-01 is so expensive.

13 upvotes 6 years ago

The conversation discusses the high cost of CB-03-01, a topical antiandrogen for hair loss, which is considered safe and remains localized upon application. It questions whether the expense is justified compared to the lower risks it poses relative to finasteride.

community How to get rid of dandruff once and for all?

in Treatment 7 upvotes 2 years ago

A 20-year-old male using Minoxidil and finasteride for 6 months and keto shampoo for 5 months saw initial improvement in dandruff, but the condition returned. He recently started using 3% salicylic acid shampoo and seeks advice for persistent dandruff, which is oily and localized to the left side of his scalp.

community Question regarding Stemoxydine

in Product 6 upvotes 1 year ago

Stemoxydine is a hair loss treatment discussed in a forum. Its effectiveness is questioned by users.

community Any success stories using Exosomes?

in Treatment 2 upvotes 2 years ago

User tried Exosomes for hair loss with no success but experienced healing in other areas. Noticed people with previous hair transplants responded well to Exosomes.

community Dr. Kyle Gillet on Dr. Andrew Huberman's podcast said dutasteride mesotherapy blocks DHT conversion only in the scalp and called it the most promising topical currently. What's the scoop?

in Treatment 25 upvotes 2 years ago

Dr. Kyle Gillet mentioned on Dr. Andrew Huberman's podcast that dutasteride mesotherapy blocks DHT conversion only in the scalp and is the most promising topical treatment. Users discussed concerns about systemic absorption and the practicality of dutasteride injections.

community Any updates or news on Gt20029?

in Chat 9 upvotes 1 month ago

There are no updates on GT20029, and concerns about its safety and effectiveness remain. The phase III trial has not started, and there are no new studies or data releases.

community Upcoming treatment ideas in the future

in Research/Science 10 upvotes 1 month ago

Exploring future hair loss treatments, including immunosuppressants for hair transplants and hair cloning, with a focus on leveraging research from other medical fields. Current treatments like finasteride and minoxidil are effective for most, but there's a call for more funding and innovation in the hair loss industry.

community Serum DHT CAN'T cause hair loss. Sebum DHT is a better measurement.

in Research/Science 19 upvotes 2 months ago

Serum DHT is mostly inactive; sebum DHT is a better measure for hair loss. Users discuss using finasteride, dutasteride, and topical treatments like KX826 and RU58841 for better scalp DHT suppression.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 120 upvotes 7 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Is this enough to regrow my lions mane and if no what am I missing?

in Chat 1 upvotes 7 months ago

A user is trying to regrow hair using a natural approach without Minoxidil or finasteride, focusing on micro-needling, red light therapy, and various oils and serums. Other users suggest that medical treatments are more effective for male pattern baldness.

community Grey Market GT20029 and Frequency of Application

in Product 9 upvotes 7 months ago

The conversation is about the potential release of GT20029 on the grey market and concerns about its safety and authenticity. One user advises waiting for the official release by Kintor.

community Sunlight: Does it Stimulate Hair Growth or Hair Loss?

in Research/Science 61 upvotes 8 months ago

The conversation discusses whether sunlight exposure affects hair growth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.

community Pyrilutamide six months update{ New Progress Pics}

in Progress Pictures 322 upvotes 1 year ago

A user shared a six-month update on hair improvement using Pyrilutamide and Minoxidil, noting significant hair regrowth and strength. Some participants questioned the legitimacy of the results and the source of Pyrilutamide.

community 6 Month Progress – Topical Fin/Min (0.3%, 6%), Weekly Microneedling 1.5mm, 40 Yrs Old

in Progress Pictures 300 upvotes 1 year ago

The 6 month progress of a 40 year old user using topical Finasteride and Minoxidil and weekly Microneedling to treat hair loss, with other users offering advice and asking questions.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Is itching related to hair loss?

in Treatment 54 upvotes 2 years ago

Hair loss, which is sometimes accompanied by itching. Treatments discussed include Minoxidil, finasteride, RU58841 and ketocazole shampoo.

community Minoxidil alternative with a week long half-life? Why isn’t it possible?

in Satire 2 years ago

This conversation discussed the potential for a hair loss treatment alternative to minoxidil, with many users debating the economic and health implications of such an option. Some suggested that finasteride could be used as an alternative, while others argued that this would ultimately not benefit pharmaceutical companies due to their reliance on planned obsolescence.

community How is there no topical anti-androgen that doesn’t go systematic?!

in Treatment 6 upvotes 4 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, Alfatradiol, and Eucapil. Topical treatments must penetrate skin and may go systemic, with effectiveness varying.

community Seems I have acquired progressive kinking of the hair, potentially brought on by minox.

11 upvotes 7 years ago

User experienced hair kinking after starting minoxidil, despite being on finasteride for two years. Another user confirmed similar issues and suggested switching brands due to propylene glycol in minoxidil.

community Has anyone had experience with PRP causing or exasperating alopecia areata?

in General 96 upvotes 3 weeks ago

A 33-year-old female with androgenic alopecia experienced alopecia areata patches after PRP treatment. She is seeking others' experiences with PRP worsening alopecia areata.

community The day they make a pill that only targets DHT production in the scalp

in Finasteride/Dutasteride 29 upvotes 1 month ago

Reducing DHT in the scalp is ideal for hair retention, with topical finasteride and dutasteride being common treatments. Some users report side effects like reduced libido, while others experiment with higher doses for regrowth.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 107 upvotes 2 months ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community Diffuse thinner regrowth over the course of 12 months

in Progress Pictures 458 upvotes 2 months ago

The user shared their 12-month hair regrowth progress using 1mg finasteride, 5mg oral minoxidil, and topical minoxidil. They also used a derma stamp weekly and treated seborrheic dermatitis with Mometasone and Nizoral.

community Ru58841 for a female w male pattern baldness

in General 166 upvotes 4 months ago

A user is considering using RU58841 for female pattern baldness and is also planning to use Minoxidil. They are hesitant to ask their doctor for spironolactone due to its cosmetic nature and are experiencing significant hair loss possibly due to stress and hormonal issues.

community I was on 2.5 mg oral minoxidil

in Progress Pictures 468 upvotes 5 months ago

User took 2.5 mg oral minoxidil, saw hair growth but stopped due to excessive body hair. Recently started finasteride and plans to update progress.

community 7 months min/dut, micro needling daily, 9 vitamins, baby shamp

in Progress Pictures 770 upvotes 7 months ago

A user shared their 7-month hair regrowth progress using Minoxidil, Dutasteride, daily microneedling, and 9 vitamins, including vitamin E, D, C, B12, biotin, omega 3, and zinc. They also massage their scalp daily and use baby shampoo.

community Hair repigmentation of poliosis circumscripta in androgenetic alopecia patient treated with exosomes and fractional picosecond laser

in Product 2 upvotes 9 months ago

Exosomes combined with fractional picosecond laser treatment were effective in treating androgenetic alopecia and promoting repigmentation in white hair patches. The role of exosomes in hair repigmentation, particularly in conditions like poliosis, is not well-studied.

community Brainstorming: upping your dermarolling game

in Research/Science 6 upvotes 11 months ago

The conversation is about enhancing dermarolling for hair loss by using topical peptides like tb-500 or GHK-Cu to aid in healing and hair growth, and whether anyone has experienced significant results from this method.

community [Serious] Experience with grey-market KX-826 (Pyrilutamide)

in Research/Science 2 upvotes 1 year ago

The user experienced reduced hair loss using grey-market KX-826 alongside Minoxidil foam, achieving better results with Minoxidil liquid but restricted to foam due to an allergy. Initial side effects included shortness of breath, racing heart, and dizziness, which subsided after the first week.

community Are there ever going to be any oral DHT blocking treatments in the future?

in Product 6 upvotes 1 year ago

The discussion revolves around the need for future oral DHT blockers for hair loss treatment that don't have the side effects of current options like Finasteride and Dutasteride. One user suggests that the future of hair loss treatment will likely be topical anti-androgens, as they can target hair follicles without affecting the entire system.