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GlossaryLipoatrophy

localized loss of fat tissue causing skin indentations

Lipoatrophy is the localized loss of fat tissue, often resulting in indentations or depressions in the skin. This condition can be caused by repeated injections, certain medications, or autoimmune diseases, and it is commonly seen in people with diabetes who use insulin injections.

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research Lipoatrophy and Severe Metabolic Disturbance in Mice with Fat-Specific Deletion of PPARγ

218 citations, October 2013 in “Proceedings of the National Academy of Sciences of the United States of America”

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

research Adipose and Hair Function: An Apparent Connection

7 citations, February 2018 in “Journal of Investigative Dermatology”

Fat tissue and a specific protein are crucial for healthy hair growth and maintenance.

research Acquired Progressive Kinking of the Hair in the Setting of Parry-Romberg Syndrome

May 2015 in “Journal of The American Academy of Dermatology”

A woman with Parry-Romberg syndrome developed new curly hair on one side of her scalp, a condition not previously linked to the syndrome.

research Alopecia Associated with Indinavir Therapy

38 citations, August 1999 in “New England journal of medicine/The New England journal of medicine”

Indinavir can cause hair loss and other skin problems.

research Management of Visible Granulomas Following Periorbital Injection of Poly-L-Lactic Acid

49 citations, July 2007 in “Ophthalmic Plastic and Reconstructive Surgery”

Surgical excision is an effective treatment for persistent nodules from poly-L-lactic acid injections.

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