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GlossaryLipoatrophy

localized loss of fat tissue causing skin indentations

Lipoatrophy is the localized loss of fat tissue, often resulting in indentations or depressions in the skin. This condition can be caused by repeated injections, certain medications, or autoimmune diseases, and it is commonly seen in people with diabetes who use insulin injections.

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research Lipoatrophy and Severe Metabolic Disturbance in Mice with Fat-Specific Deletion of PPARγ

218 citations , October 2013 in “Proceedings of the National Academy of Sciences of the United States of America”

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

research Coexistence of Acquired Localized Hypertrichosis and Lipoatrophy After Lupus Panniculitis

10 citations , April 2004 in “Journal of the American Academy of Dermatology”

research Adipose and Hair Function: An Apparent Connection

7 citations , February 2018 in “Journal of Investigative Dermatology”

Fat tissue and a specific protein are crucial for healthy hair growth and maintenance.

research Acquired Progressive Kinking of the Hair in the Setting of Parry-Romberg Syndrome

May 2015 in “Journal of The American Academy of Dermatology”

A woman with Parry-Romberg syndrome developed new curly hair on one side of her scalp, a condition not previously linked to the syndrome.

research Dermatological Issues in a Child with Diabetes Mellitus

January 2003 in “Springer eBooks”

Children with diabetes often have skin problems, which can be better managed with good blood sugar control.

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