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Glossary Genetic Inheritance

process by which parents pass genes to offspring

Genetic inheritance, also known as heredity, is the process by which genetic information is passed from parents to their offspring through their genes. This transfer of genetic material determines various traits and characteristics, such as eye color, hair type, and susceptibility to certain diseases, including conditions like alopecia.

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Research

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research A Study on the Pattern of Genetic Inheritance of Polycystic Ovarian Syndrome

1 citations , November 2014 in “British journal of medicine and medical research”

This study investigated the inheritance patterns of PCOS and found that 33% of participants had metabolic syndrome, which was more prevalent in first-generation relatives.

research Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia

195 citations , June 2005 in “American Journal of Human Genetics”

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

research Androgenetic Alopecia in Men: An Update On Genetics

May 2024 in “Indian Journal of Dermatology”

In this review, an association was reported between early-onset androgenetic alopecia and several health conditions like obesity and cardiovascular disease, with genetic and therapeutic research ongoing to improve treatment.

research A genetic electrophoretic variant of high-sulfur hair proteins for forensic hair comparisons. I. Characterization of variant high-sulfur proteins of human hair.

February 1989 in “PubMed”

This study found a genetic electrophoretic variant in high-sulfur proteins from human hair, which was more prevalent in the Japanese samples compared to Caucasian samples, suggesting an autosomal inheritance pattern.

research Dissection of genetic variation and evidence for pleiotropy in male pattern baldness

58 citations , December 2018 in “Nature Communications”

This study found that male pattern baldness in European males is strongly heritable and associated with genetic markers linked to earlier puberty, bone density, and pancreatic function.

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community A man in his 80s with full head of hair.

473 upvotes 5 months ago

Genetics play a major role in hair loss, with some people keeping a full head of hair into old age without using treatments like minoxidil or finasteride. Many express frustration over their own hair loss and the perceived unfairness of genetic differences.

community The pessimism about the Crisp Cas 9 is excessive

12 upvotes 11 months ago

CRISPR Cas9 could potentially treat baldness by targeting specific genes in hair follicles without affecting other body functions. There is optimism about its future use, despite ethical concerns and the current reliance on treatments like minoxidil and finasteride.

community started balding at 15, currently 19 and I'm honestly so depressed

in Chat 9 upvotes 6 months ago

A 19-year-old is struggling with hair loss despite using minoxidil and finasteride, feeling depressed and lacking confidence. Suggestions include trying dutasteride, topical treatments, hair transplants, or accepting baldness.

community I want it all to end so badly. I’ve lost my 20s to this

in Chat 73 upvotes 4 months ago

A person struggling with hair loss is using treatments like dutasteride, oral minoxidil, and has had a hair transplant but remains deeply unhappy. Others suggest alternative treatments, acceptance, and focusing on other life aspects, emphasizing mental health and therapy.

community Male pattern baldness is not cosmetic.

224 upvotes 10 months ago

Male pattern baldness is linked to health risks and should be treated medically. Finasteride is effective and should be insurance-covered.

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