7 citations
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January 2022 in “Plants” This study found that extracts from the rice variety Bue Bang 3 CMU, particularly the husk and bran, demonstrated antioxidant, anti-inflammatory, and anti-androgenic properties, suggesting potential use in treating androgenetic alopecia.
May 2024 in “Journal of Agricultural and Food Chemistry” In a study using mice, researchers observed that Cacumen platycladi fermented with Lactiplantibacillus plantarum CCFM1348—both as postbiotics and synbiotics—promoted hair growth, potentially by engaging the Wnt/β-catenin signaling pathway and enhancing growth factor expression.
This study investigated the effect of Astragalus membranaceus extract on hair regrowth in C57BL/6 mice with natural hair loss in the telogen phase, but specific results are not provided in the abstract.
This review outlines diagnostic and treatment approaches for hirsutism, highlighting spironolactone or cyproterone acetate with oral contraceptives as the most effective therapy, and reports no new empirical results.
1 citations
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May 2012 in “International Conference on Biomedical Engineering and Biotechnology” This study suggests that TGF-β receptor 1 may play a role in deer antler skin cell differentiation and dermis fibroblasts' rapid proliferation, potentially aiding the alignment of skin and cartilage growth rates in sika deer antlers.
May 2026 in “Reactions Weekly”
April 2019 in “Advances in integrative medicine” This study found that the highest rebound value in concrete with high volume slag occurs with 40% slag content, 10–20 mm basalt aggregates, and greater carbonation depth.
23 citations
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March 2014 in “International Journal of Molecular Sciences” The study observed that testosterone reduced knee range of motion in ovariectomized female rats, potentially by downregulating specific relaxin receptor isoforms, with its effects mediated via dihydro-testosterone.
November 2024 in “Journal of Investigative Dermatology” Reishi mushroom extract may help treat hair loss.
19 citations
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June 2021 in “The world journal of men's health” This review examines the negative effects of anabolic-androgenic steroid use on the male reproductive system, including impaired testosterone production, sperm production issues, and adverse metabolic consequences without reporting new clinical results.
68 citations
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May 1991 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that both cyproterone acetate and spironolactone effectively reduced hair diameter and plasma testosterone levels in hirsute women, with no significant differences between the two treatments.
June 2022 in “Jurnal Health Sains” This review discusses plant-based alternatives for hair tonic formulations to address hair loss and contains no new clinical results, advocating for plant extracts as safer options than synthetic ingredients.
58 citations
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July 1974 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that cyproterone acetate, given with ethinyl oestradiol, significantly reduced hirsutism in women after 12 months, although improvements reversed once cyproterone acetate was stopped.
January 2022 in “Turk Dermatoloji Dergisi” This placebo-controlled study found that topical procyanidin B2 significantly increased total and anagen hair counts in men with androgenetic alopecia over 16 weeks compared to placebo, suggesting it as an effective and safe treatment option.
53 citations
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July 2014 in “American Journal of Physiology-Endocrinology and Metabolism” This study found that testosterone-enanthate increased red blood cell production and altered iron homeostasis in older hypogonadal men without being affected by finasteride, indicating these effects do not require type II 5α-reductase enzyme activity.
August 2025 in “ACS Omega” This study synthesized and evaluated hydroxycinnamate derivatives for their ability to inhibit human SRD5A1, finding that three compounds showed significant inhibitory activity and low cytotoxicity. Compound 10a notably reduced SRD5A1 protein expression in cells, suggesting potential for nonsteroidal treatment of androgen-related conditions.
12 citations
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January 1998 in “Endocrine journal” Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
May 2024 in “Current perspectives on medicinal and aromatic plants” This mini review explores the potential of herbal testosterone 5α-reductase inhibitors for treating androgenetic alopecia, suggesting they might offer fewer side effects and better tolerability than traditional treatments like finasteride and minoxidil.
January 2026 in “http://isrctn.com/” The supplement may improve hair growth and quality in women with mild to moderate hair loss.
January 2025 in “European Journal of Pharmacology” This study found that forsythoside A, a compound from Forsythia suspensa, may counteract DHT-induced hair regrowth inhibition by selectively inhibiting TRPV3 channels.
3 citations
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June 2009 in “The journal of alternative and complementary medicine/Journal of alternative and complementary medicine” This letter discusses the potential of green tea extract as a treatment for hirsutism but reports no clinical outcomes.
4 citations
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January 2015 in “Pharmacology” This report describes a case where a food supplement containing Serenoa repens extract was associated with hot flashes and menarche in a 10-year-old girl being treated for hirsutism.
9 citations
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March 2009 in “European Journal of Dermatology” In this animal study, the researchers found that Schisandra nigra extract may promote hair growth by extending the anagen phase and reducing TGF-beta2 expression.
May 2019 in “Eurasian Journal of Biosciences” In this study, researchers observed that fenugreek aqueous extract was more effective than its alcohol extract in inhibiting the growth of bacteria associated with acne, particularly gram-positive bacteria like Staphylococcus epidermidis and Staphylococcus aureus.
26 citations
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November 2002 in “Planta medica” In this study, the methanol extract of Cercidiphyllum japonicum heartwood was found to stimulate the proliferation of mouse hair epithelial cells, with several isolated compounds showing significant proliferative activities.
March 1997 in “The Lancet” Hirsutism is abnormal male-pattern hair growth in females due to excess androgens.
March 2026 in “Seven Editora eBooks” This study systematically reviewed the use of topical testosterone products such as creams, gels, and patches, finding they effectively raise serum testosterone but pose significant systemic risks like acne and gynecomastia, necessitating careful medical oversight.
January 1989 in “Oxford University Research Archive (ORA) (University of Oxford)” This study found that spironolactone effectively reduced hair growth in hirsute women over 12 months and was generally well tolerated.
2 citations
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January 2019 in “Research journal of pharmacy and technology” This study found that the ethanol extract of Sterculia urceolata and its fractions stimulated hair growth in male rabbits, with a 15% concentration of the water fraction showing the most significant effect.
August 2025 in “Intisari Sains Medis” This study found that in healthy individuals, TGF-β1 levels in platelet-rich plasma are significantly higher when extracted using the buffy coat method compared to the pure method, with additional gender differences observed only in the buffy coat PRP.