Unlocking The Potential Of Ganoderma Lucidum: Exploring The Efficacy Of Reishi Mushroom Extract In Promoting Hair Growth And Scalp Health

The study explores the efficacy of Ganoderma lucidum (reishi mushroom) extract in promoting hair growth and scalp health by inhibiting 5α-reductase isoform 2 (5αR2), a key enzyme involved in hair loss. Using an in vitro model with murine fibroblast BALB/3T3 cells pre-treated with testosterone, the researchers found that G. lucidum significantly inhibited 5αR2 expression, with effects comparable to known botanicals like Serenoa repens, Ajuga reptans, and the pharmaceutical finasteride. These findings suggest that G. lucidum could be effective in treating hair loss, though further in vivo studies are needed to confirm these results.