8 citations
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September 2024 in “Food Science & Nutrition” This review discusses the benefits of β-sitosterol, a plant compound found in nuts and seeds, which may lower "bad" cholesterol and help prevent heart disease, cancer, and diabetes, but notes the lack of clinical studies on its safety and effectiveness in humans.
48 citations
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January 2003 In this study, researchers isolated and identified diverse endophytes from plants in Asia, finding that these microorganisms have significant potential for producing useful metabolites, including enzymes and antibiotics.
August 2023 in “Malaysian Journal of Medicine and Health Sciences/Malaysian journal of medicine and health sciences” This study found that aqueous extract of Pueraria mirifica, when administered to a rat model, significantly reduced prostate weight, prostatic index, and serum dihydrotestosterone levels, while also improving prostate histomorphology, suggesting its potential as an anti-BPH treatment.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review compiles existing knowledge on the traditional uses, phytochemistry, and pharmacological activities of Eclipta alba, a plant with potential health benefits traditionally used in Ayurveda and other healing systems, encouraging further exploration of its therapeutic potential.
December 2023 in “Bulletin of Pharmaceutical Sciences Assiut” In this study, GC/MS analysis revealed variability in the quality of Syrian herbal formulations for BPH, with variations in tocopherol content, presence of parabens, and shortages of certain phytosterols.
10 citations
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October 2020 in “Microscopy and Microanalysis” This study found that resveratrol significantly alleviated testicular damage in male rats caused by finasteride, which otherwise led to decreased testosterone levels and various histopathological alterations in the testes.
January 2014 in “Side effects of drugs annual” This review discusses the 2011 publications on the side effects of sex hormones and related compounds, without reporting new clinical results.
11 citations
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August 2020 in “Diabetes” This study found that testosterone enhances insulin secretion in human pancreatic islets by being converted into DHT and E2, processes that are necessary for this effect.
4 citations
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January 2018 in “JBRA assisted reproduction” This study found that orlistat significantly reduced weight and total testosterone levels in Iranian women with polycystic ovary syndrome after 12 weeks of treatment.
September 2023 in “Journal of the American Academy of Dermatology” CTP-543 significantly improved eyebrow and eyelash regrowth and patient satisfaction in adults with alopecia areata.
14 citations
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December 1998 in “The Journal of Clinical Endocrinology and Metabolism” This study found that MENT is 10 times more potent than testosterone in suppressing gonadotropins and contributing to anabolism in monkeys, with a potentially wider therapeutic index for human androgen replacement and male contraception.
February 2025 in “Global Academic Journal of Pharmacy and Drug Research” This study reported that compounds from the root of Beta vulgaris, specifically 4-picoline and Betalain, showed potential as effective anti-hair loss treatments by demonstrating significant inhibitory activity against the enzyme 5α-reductase in a computational molecular docking study.
July 2025 in “Dermatologica Sinica” In this study, compound glycyrrhizin promoted hair regrowth in a testosterone-induced alopecia mouse model and increased human hair dermal papilla cell proliferation, likely through activating the Wnt/β-catenin pathway.
January 2018 in “Journal of the American Academy of Dermatology” This letter discusses a previous study on tofacitinib for alopecia areata, questioning its statistical analysis and suggesting that steroids may have influenced results, but it reports no new clinical findings.
December 2018 in “Jurnal Farmamedika (Pharmamedica Journal)” This study found that a combination of ethanol extract from watermelon white skin and liquid from kepok banana tree trunk resulted in greater hair growth length in rats compared to Minoxidil.
January 2024 in “Life sciences” This study observed that in spontaneously hypertensive rats, testosterone's effects on endothelium-dependent vasodilation involved reduced nitric oxide levels, increased oxidative stress, and greater reliance on endothelium-dependent hyperpolarization, with variations in these responses noted when testosterone was combined with either anastrozole or finasteride.
14 citations
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January 2019 in “Journal of Natural Medicines” This study found that certain compounds from Chaga mushrooms stimulated the proliferation of human hair follicle cells more effectively than minoxidil, suggesting potential for hair-growth treatments.
44 citations
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June 1985 in “Fertility and sterility” This study suggests that combination drug therapy with spironolactone and either oral contraceptives or dexamethasone effectively manages unresponsive hirsutism, with eight of nine patients achieving satisfactory clinical responses.
5 citations
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December 2011 in “Drug Research” This study found that cortexolone 17α-propionate showed strong topical antiandrogenic activity, outperforming progesterone and several known antiandrogens, but lacked systemic antiandrogenic effects in animal models.
This Phase II trial found that topical GT20029 significantly increased hair count and width at 12 weeks in Chinese men with androgenetic alopecia compared to placebo, with good tolerability and similar adverse event incidence across groups.
January 2019 in “Oncogen” This report suggests that for prostate cancer patients with cardiovascular disease, prescribing the GnRH antagonist degarelix may reduce cardiac events compared to using GnRH agonists, although prescribing should consider potential cardiac risks, particularly in patients with pre-existing conditions or older age.
March 2014 in “The Journal of Urology” This study observed that long-term treatment with 5ARIs in men with LUTS/BPH was linked to worsening sexual function, whereas doxazosin alone had minimal negative impact.
June 2026 in “International Journal of Ayurvedic Medicine” This randomized clinical trial observed that Facia Men’s capsule significantly reduced hair shedding in men with androgenetic alopecia over 12 weeks without affecting renal or liver function, though a small change in blood glucose suggests monitoring metabolic health.
56 citations
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April 2003 in “Fertility and Sterility” This study found that while cyproterone acetate, finasteride, and spironolactone had similar short-term effects in treating idiopathic hirsutism, spironolactone provided more lasting benefits one year after treatment.
October 2018 in “Elsevier eBooks” This source reports that Serenoa repens may be an effective and safe natural remedy for treating benign prostatic hyperplasia, possibly working through mechanisms like apoptosis stimulation, 5-alpha-reductase inhibition, and blocking DHT receptor interactions, with minimal side effects.
November 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This promotional text about Alpha Xtra Boost does not report any new research findings or clinical results.
3 citations
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July 2025 in “International Immunopharmacology”
255 citations
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October 1985 in “The Journal of Clinical Endocrinology & Metabolism” This study concluded that albumin-bound testosterone is biologically important and significantly contributes to testosterone bioavailability in women receiving spironolactone.
2 citations
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December 2020 in “Phytomedicine plus” In this study, researchers found that taking Saw palmetto and Pygeum africana supplements for five days altered the urinary steroid profile in a way that may interfere with the steroidal module of the Athlete Biological Passport.
July 2023 in “Skin Research and Technology” This study reports that combining baricitinib with low-dose cyclosporine and steroids resulted in effective and safe treatment for a case of alopecia totalis, maintaining hair regrowth without adverse effects.