May 2023 in “IntechOpen eBooks” This review outlines the role of testosterone in male sexual development and its therapeutic use for male hypogonadism, covering its biosynthesis, secretion, metabolism, and various biological actions, but does not report specific study results.
January 2026 in “Frontiers in Pharmacology” This study found that anwuligan, an active ingredient in BaoHeWan, may promote hair regeneration in mice by activating the Wnt/β-catenin signaling pathway and enhancing hair follicle cell proliferation.
22 citations
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October 2020 in “Frontiers in Cell and Developmental Biology” This study found that resveratrol and fisetin promoted hair growth in mice by inducing telomerase reverse transcriptase expression, which activates hair follicle stem cells and transitions follicles from a resting to a growth phase.
20 citations
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December 2015 in “Der Urologe” Combining medications is more effective for treating benign prostatic syndrome symptoms.
90 citations
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July 2009 in “PTR. Phytotherapy research/Phytotherapy research” In this study, spearmint tea significantly reduced testosterone levels and improved self-reported hirsutism in women with PCOS, but did not change objective hair growth scores over the short trial period.
July 2021 in “Hair transplant forum international” This review discusses the use of fenugreek seeds for managing androgenetic alopecia and finds insufficient evidence to recommend their routine use, highlighting necessary caution due to potential drug interactions.
September 2022 in “PubMed” Entadfi, a mix of finasteride and tadalafil, is used for BPH.
August 2022 in “Ad-Dawaa' Journal of Pharmaceutical Sciences” This study found that a combination of H. rosa-sinensis L. and B. racemosa extracts produced the most hair follicles in stress-induced alopecia in male Wistar albino rats.
112 citations
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April 2009 in “Cochrane library” This review found some evidence suggesting that spironolactone can effectively reduce hirsutism in women but did not support its use for treating acne vulgaris.
12 citations
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December 2002 in “Fertility and Sterility” In this study, a combination of spironolactone and finasteride was found to significantly improve hirsutism scores without increasing side effects compared to spironolactone alone.
This study found that Clitocybin A from Clitocybe aurantiaca significantly increased the proliferation of immortalized rat dermal papilla cells, suggesting potential hair growth-promoting effects in a laboratory setting.
43 citations
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November 1975 in “Archives of Dermatology” This review discusses testosterone metabolism in human skin and its link to androgenetic alopecia, acne vulgaris, and idiopathic hirsutism, but it presents no new results.
January 2025 in “Journal of Cosmetic Dermatology” This study suggests that addressing hormonal, stress, and metabolic factors with vitamins, minerals, and botanicals, which has improved hair growth in women, might also benefit men experiencing hair thinning.
September 2023 in “International Journal of Trichology” This case report describes a successful treatment of alopecia universalis in a 37-year-old female using oral tofacitinib, along with other therapies, resulting in significant hair regrowth without notable safety concerns.
3 citations
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February 2021 in “Evidence-based Complementary and Alternative Medicine” This study observed that oral administration of BeauTop, a Chinese herbal medicine, significantly increased hair growth indicators, including VEGF expression, hair follicles, and hair coverage in C57BL/6 mice.
November 2024 in “Journal of Investigative Dermatology” Ursolic and shikimic acid together boost hair growth better than alone.
July 2026 in “International Journal of Molecular Sciences” This study found that TSG-enriched Polygonum multiflorum extract, optimized through microwave-assisted and chromatographic methods, promotes hair regrowth in a mouse model of androgenetic alopecia via 5α-reductase inhibition and Wnt/β-catenin pathway activation, suggesting its potential as a natural treatment.
1 citations
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January 2020 in “Indian Journal of Pharmaceutical Sciences” This review reports limited evidence on topical treatments for beard enhancement, with topical minoxidil, testosterone gel, and tretinoin showing potential but requiring further study.
23 citations
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September 2021 in “Frontiers in Cellular and Infection Microbiology” This review highlights the mixed roles of testosterone in COVID-19, noting both potential benefits through anti-inflammatory effects and risks due to increased virus entry, with low testosterone linked to increased severity.
June 2026 in “Kocatepe Veterinary Journal” This study found that periodic intratesticular PRP administration may slightly enhance testicular development in male lambs, indicated by increased testicular blood flow, length, and reduced resistance index compared to saline.
January 2024 in “Al-Ameed journal for medical research and health sciences” This review summarizes the latest evidence on testosterone, detailing its clinical indications, diagnostic tests, and impacts on various male organs, while also noting its association with aging, metabolic disorders, and increased mortality risk due to androgen deficiency.
2 citations
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September 2023 in “Journal of the American Academy of Dermatology” CTP-543 effectively promotes hair regrowth in adults with moderate to severe alopecia areata.
December 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”
2 citations
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August 2010 in “Journal of Scientific Research” This study provides detailed macro and microscopical observations of Tridax procumbens Linn. leaf, which could aid in its identification.
38 citations
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July 2012 in “international journal of endocrinology and metabolism” This review discusses the clinical use of anti-androgen medications and highlights emerging evidence supporting plant-derived anti-androgens like spearmint tea for managing PCOS, but reports no new clinical results.
2 citations
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October 2018 in “Archives of Dermatological Research” The researchers reported that topical tofacitinib in mice increased hair follicles in the growth phase and boosted noggin and BMP4 mRNA expressions, compared to a vehicle and minoxidil.
May 2026 in “Global Translational Medicine” This study found that ethanol extract of Syzygium aromaticum (clove) leaves significantly improved lipid profiles and increased body weight in testosterone-induced benign prostatic hyperplasia rats, suggesting potential anti-hyperlipidemic effects and modulation of body weight through metabolic activity.
This study found that a combination of spironolactone and oral contraceptive pills may improve hirsutism and hormonal profiles in women, although some experienced side effects such as persistent nausea.
2 citations
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January 2023 in “BioMed Research International” The researchers reported that a 5% Beta vulgaris L. extract nanogel showed better antialopecic activity in testosterone-induced alopecia in mice compared to a 2.5% concentration.
June 2007 in “Endocrinology and Metabolism Clinics of North America” This study reports that incomplete information in a reverse supply chain can lead to efficiency losses, but a two-part tariff contract for the remanufacturer may improve performance by eliciting private information from collectors.