1 citations
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May 2021 in “International Journal of Dermatology” This article presents the surgical technique of long hair follicular unit excision (FUE) in hair transplantation and reports procedural and outcome data for 134 patients, without evaluating clinical outcomes.
1 citations
,
January 2020 This review outlines the evolution of hair restoration techniques, emphasizing follicular unit extraction over traditional methods due to its reduced scarring and pain, but provides no new clinical findings.
1 citations
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September 2016 in “Indian Journal of Plastic Surgery” This article describes a modified follicular unit extraction technique using a reverse rake scalp elevator, which may reduce follicular transection rates in hair transplantation from the lower occipital donor region.
1 citations
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January 2006 in “Dermatologic Surgery” The SAFE System may reduce hair transplant transection rates but has been critiqued for not being as minimally invasive as claimed.
July 2025 in “Chinese Journal of Dermatology” This study concluded that the effectiveness and safety of a domestic follicular extraction system were similar to conventional follicular unit excision in patients undergoing hair transplant surgery for androgenetic alopecia.
January 2024 in “Advances in Cosmetic Surgery” This review highlights that robotic hair transplantation reliably and efficiently extracts follicular units with transection rates comparable to manual methods, potentially allowing more physicians to offer hair restoration without needing additional staff, and notes ongoing software advancements that could enhance aesthetic results.
December 2023 in “Dermatologic Surgery” The researchers reported that using a skin-responsive FUE device in nonscalp hair transplantation significantly reduced graft transection rates compared to older methods, improving patient satisfaction and surgeon willingness.
December 2023 in “Clinical, cosmetic and investigational dermatology” This study found that no-shave long hair-follicular unit excision using a skin-responsive device, without recess-tipped punches, yielded low graft transection and shaft break rates, improved procedure speed, and increased surgeon willingness.
October 2022 in “Hair Transplantation” This review discusses the choice between follicular unit transplantation (FUT) and follicular unit excision (FUE) in hair restoration surgery, highlighting their respective advantages and how improved techniques have increased FUE's popularity despite equivalent aesthetic results with FUT.
December 2008 in “Dermatologic Surgery” This study found that the novel powered FUE (P-FUE) technique reduced harvesting time and graft transection rates in hair restoration compared to manual FUE, with broader patient applicability.
June 2006 in “The American Journal of Cosmetic Surgery” Advancements in cosmetic and reconstructive surgery improve techniques and patient satisfaction.
June 2002 in “Seminars in Cutaneous Medicine and Surgery” Using a microscope during hair transplants cuts damage to follicles in half and could improve hair growth.
248 citations
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November 2011 in “The EMBO Journal” This study found that Wnt1/βcatenin signaling plays a crucial role in activating the epicardium and cardiac fibroblasts, which supports cardiac repair following acute ischemic injury.
176 citations
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June 2019 in “Cells” This review discusses dermal cell heterogeneity in wound healing and scar formation, highlighting the varied roles of different fibroblasts and the potential of skin substitutes without presenting new clinical results.
132 citations
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August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” This review discusses the roles of TGF-β family signaling in regulating normal and cancer stem cells and highlights the need for further research to develop potential cancer treatments; it reports no new results.
130 citations
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December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, different types of catagen in the C57BL/6 mouse model exhibited varying effects on hair follicle melanocytes and melanin distribution, with spontaneous and dexamethasone-induced catagen showing pigment incontinence, while cyclophosphamide-induced catagen retained dendritic melanocytes but increased ectopic melanin.
81 citations
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February 2019 in “Experimental & Molecular Medicine” This review examines PAK4 signaling pathways in prostate cancer, Parkinson's disease, and melanogenesis, focusing on the potential role of the PAK4-CREB axis, without reporting new clinical results.
80 citations
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April 2018 in “Trends in Molecular Medicine” This review discusses the roles of interferon-γ and PPAR-γ-mediated signalling in scarring alopecia, suggesting these pathways as potential therapeutic targets, but it reports no new empirical results.
76 citations
,
June 2015 in “Journal of biomedical science” This study demonstrated that dominant mutations in mouse gasdermin A3 disrupt mitochondrial oxidative stress regulation, suggesting a gain-of-function effect on epidermal differentiation.
70 citations
,
July 2016 in “Aging” This study suggests that dermal adipocytes might play a key role in skin aging due to their transformation into fibrotic structures in chronically photo-damaged skin.
66 citations
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December 1999 in “Journal of Investigative Dermatology” New mutations in the hairless gene may cause hair loss and affect bone development.
41 citations
,
September 2012 in “Cellular and Molecular Life Sciences” This review summarizes the current understanding of microRNAs in skin biology, highlighting their roles in processes like wound-healing and aging, without presenting any new experimental results.
38 citations
,
January 2019 in “International Journal of Women's Dermatology” This review discusses potential therapeutic options for frontal fibrosing alopecia by exploring distinct signaling pathways and cellular players, but reports no new clinical findings and emphasizes the need for further trials.
36 citations
,
April 2016 in “Biochimie” This study shows that the concentration of epidermal growth factor (EGF) is crucial for determining whether mink hair follicles are promoted or inhibited in vitro, with involvement of the Notch signaling pathway in DP cell proliferation.
32 citations
,
February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports the cloning and sequencing of two type II hair-specific keratin genes, ghHb1 and ghHb6, located on chromosome 12q13, which are expressed during hair growth.
30 citations
,
November 2018 in “EMBO Reports” This study found that the Ovol2-Zeb1 regulatory circuit is crucial for controlling directional migration and proliferation in epithelial cells, facilitating skin regeneration and repair in mice.
28 citations
,
March 2014 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society” This study introduces the multiple papillary centres model, offering a new explanation for hair twisting by combining known hair morphology features with differential growth rates caused by dermal papillae.
24 citations
,
November 2019 in “Experimental Dermatology” This review synthesizes current research on PPAR-γ signaling in hair follicle biology and its potential role in treating hair growth disorders like scarring alopecia and hirsutism, but reports no new clinical results.
24 citations
,
December 2016 in “Stem Cell Research & Therapy” This study found that P311 triggers transdifferentiation of epidermal stem cells into myofibroblast-like cells via TGFβ1/Smad signaling during wound healing.
23 citations
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October 2018 in “Australasian Journal of Dermatology” This review highlights that frontal fibrosing alopecia’s increasing incidence may involve immune, genetic, hormonal, and environmental factors, yet its pathogenesis remains complex and not fully understood.