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Implanting hair-follicle stem cells in mice brains helped repair brain bleeding and reduced brain inflammation.

Implanted special stem cells from hair follicles helped heal wounds faster and with less scarring in mice.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

FLRG and follistatin have different roles in wound healing.

ILK is essential for skin development, pigmentation, and healing.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

Autoimmune diseases cause the immune system to attack the body, and management varies as some are curable and others are not.

Autoimmune diseases cause the immune system to attack the body, and management varies as some are curable and others are not.

K6/ODC transgenic mice are effective for quickly identifying cancer-causing chemicals.

LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.

Animal models help study psoriasis but have limitations and don't fully mimic the human disease.

Animal models, especially mice, are essential for advancing hair loss research and treatment.

A gene mutation in mice causes permanent hair loss and skin issues.

Too much thymosin beta4 causes weird teeth and more hair growth in mice.

Proteolytic enzymes damage hair follicles by detaching stem cells.

Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.

Mice with human chymase had a higher death rate when exposed to a toxin compared to normal mice.

Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.

Researchers developed a mouse model that tracks hair growth using bioluminescence, improving accuracy in studying hair cycles.

SV40 T antigen in hair follicles causes abnormal hair and health issues in mice.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

GFP transgenic mice help study cell origins in skin grafts.

Selenium can be toxic to animals, causing serious health issues, especially in horses.

Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Overexpressing ornithine decarboxylase and v-Ha-ras in keratinocytes leads to invasiveness and malignancy.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.