May 2026 in “Journal of Functional Foods” In this study of women with polycystic ovary syndrome, 12 weeks of daily ginger supplementation significantly reduced total testosterone and improved menstrual irregularities compared to placebo, suggesting potential as a natural therapeutic approach, although larger studies are needed.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this cross-sectional study at a tertiary care hospital, researchers found a significant correlation between cutaneous manifestations like hirsutism and acne and biochemical hyperandrogenism levels in women with PCOS, suggesting these skin conditions can predict elevated androgen levels.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that hirsutism and acne are strong predictors of biochemical hyperandrogenism in women with polycystic ovary syndrome.
September 2021 in “Conference Proceedings” This study observed that hyperandrogenism in men manifests with varying symptoms, where older men may have high total testosterone due to increased SHBG without elevated free testosterone, while younger men often show signs like acne and alopecia with elevated DHT or testosterone.
April 2020 in “Journal of the Endocrine Society” This case report describes the first known instance of a testosterone-secreting steroid cell ovarian tumor causing pulmonary embolism and erythrocytosis in a postmenopausal woman, highlighting its potential role as a rare cause of hypercoagulable state.
December 2020 in “Journal of Skin and Sexually Transmitted Diseases” This study found no significant correlation between serum testosterone or DHEAS levels and the severity of acne or FPHL in a localized female population, but noted most patients had low testosterone levels.
23 citations
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April 1993 in “Gastroenterology” This study reported a case where cyclosporine treatment in a child led to remission of ulcerative colitis and regrowth of scalp and body hair, suggesting a possible connection between the disorders.
17 citations
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August 2003 in “Ultrasound in Obstetrics and Gynecology” This review discusses the complexities of diagnosing polycystic ovary syndrome and reports no new results; the authors suggest a thorough and careful diagnostic approach to avoid misdiagnosis and unnecessary tests.
4 citations
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March 2020 in “JAAD Case Reports” This case report describes a 47-year-old male with rare total melanonychia linked to vitamin B12 deficiency, whose nail discoloration and constitutional symptoms improved following vitamin B12 supplementation.
2 citations
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January 2019 in “BMC Cancer” This meta-analysis suggests that any pattern of male baldness may be associated with a decreased risk of testicular cancer, with stage II hair loss providing the strongest protective effect.
1 citations
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November 2023 in “Journal of ovarian research” In this study involving rats with letrozole-induced polycystic ovary syndrome, Agaricus subrufescens significantly reduced blood glucose, total cholesterol, testosterone levels, and renal markers, suggesting its potential protective effects on both metabolic and reproductive parameters.
December 2022 in “Türk biyokimya dergisi” The conclusions are: fecal short-chain fatty acids may help prevent cancer, fiber intake can reduce obesity, weight loss is hard for obese people, low BMI cancer patients are more prone to chemotherapy side effects, intermittent fasting benefits gut health, cherry laurel has health benefits in rats, certain gene variations can increase stress in hair loss patients, fecal acids can affect blood sugar levels, cold agglutinin can affect blood test results in autoimmune patients, and people with Crohn's disease have higher levels of a certain chemical in their blood.
January 2015 in “Springer eBooks” This chapter describes two simple, noninvasive methods — the pull test and modified wash test — which can diagnose and assess the severity of female hair loss, including conditions like telogen effluvium and androgenetic alopecia.
March 2014 in “Journal of the American Academy of Dermatology” Alopecia areata is relatively common in children, has a variable course, and shows different responses to treatment; thyroid testing is recommended for those affected.
October 2010 in “Journal of Men's Health” Larger prostate size in older men may be linked to poorer semen quality and fertility issues.
21 citations
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January 2021 in “Therapeutic Advances in Endocrinology and Metabolism” The researchers suggest that testosterone levels might influence COVID-19 susceptibility and severity, with low levels potentially protecting against infection but possibly worsening severe disease due to cytokine storm activation.
4 citations
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August 2024 in “PLoS ONE” In this study, researchers reported that both progestin-only injectable contraceptives, DMPA-IM and NET-EN, significantly decreased serum testosterone and SHBG levels among HIV-negative women in South Africa, yet this did not explain prior findings of no reduction in risky sexual behavior or sexual function.
2 citations
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January 2023 in “BioMed Research International” The researchers reported that a 5% Beta vulgaris L. extract nanogel showed better antialopecic activity in testosterone-induced alopecia in mice compared to a 2.5% concentration.
October 2018 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that in women with PCOS in Port Harcourt, Nigeria, glucose homeostatic disorders were common, particularly among those with higher testosterone levels, suggesting the need for glucose disorder screening in this population.
May 2017 in “Endocrine Abstracts” This study found that in HIV-infected men, erectile dysfunction was influenced by the duration of HIV infection but not associated with serum testosterone or HAART therapy.
9 citations
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April 2023 in “World Journal of Clinical Cases” Test liver enzymes and triglycerides every 5-6 months, and cholesterol levels in the first two months for acne patients on isotretinoin.
2 citations
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April 2007 in “Journal of Labelled Compounds and Radiopharmaceuticals” This article discusses the preparation of tritium-labeled testosterone metabolites and reports no new experimental findings.
1 citations
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January 2018 in “AUSTRALIAN JOURNAL OF BASIC AND APPLIED SCIENCES” In this study, the ethanol extract of Zapoteca portoricensis stem significantly reduced markers of testosterone-induced benign prostate hyperplasia in male albino rats without harming liver and kidney function.
1 citations
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May 2023 in “Fertility and sterility” In this cohort study of young Danish men, self-reported older age at voice break was linked to certain reproductive hormone changes that suggest reduced male fecundity, but associations with semen characteristics and testicular volume were not statistically significant.
July 2022 in “World Journal of Advanced Research and Reviews” This study found that methanolic extract of Cordia plathytyrsa increased testosterone levels in male rats but did not affect other evaluated metabolic parameters.
January 2024 in “Journal of Applied Health Sciences and Medicine” In this study, Nephrolepis biserrata extract significantly improved fertility indices in male Wistar rats with testosterone propionate-induced benign prostatic hyperplasia, showing increased sperm count and reduced prostate weight, suggesting potential pro-fertility benefits for BPH-related infertility.
July 2022 in “Zenodo (CERN European Organization for Nuclear Research)” In this animal study, methanolic extract of *Cordia plathytyrsa* increased testosterone synthesis in male rats but had limited effects on metabolic parameters, while *Piptadeniastrum africanum* raised triglycerides and both extracts did not cause oxidative stress.
February 2022 in “Journal of Cosmetic Dermatology” This study found that pre-treating hair with argan oil reduced protein loss and provided protection against oxidative damage, supported by both ATR spectrum analysis and protein measurements.
March 2023 in “Archives of Physical Medicine and Rehabilitation” This pilot study suggests that high-dose testosterone plus finasteride increased lower-extremity bone mineral density in men with impaired gait and low to low-normal testosterone following chronic incomplete spinal cord injury.
October 2020 in “System Dynamics Review” This study models the pathways of nandrolone and its metabolites in the body and suggests methods to counteract finasteride's role in enabling PED users to cheat drug tests.