42 citations
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January 2005 in “Applied spectroscopy” In this study, hair samples from breast cancer patients showed increased β-sheet structures and lipid content, with spectral markers successfully identifying cancer in a blind test but also producing false positives.
July 2024 in “Journal of Investigative Dermatology” Machine learning can use blood tests to help predict moderate-to-severe alopecia areata.
February 2021 in “International Journal of Science and Research (IJSR)” This study found that the total testosterone/dihydrotestosterone ratio is significantly higher in women with polycystic ovary syndrome and is associated with a worse metabolic profile in both PCOS and healthy women.
4 citations
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January 2018 in “JBRA assisted reproduction” This study found that orlistat significantly reduced weight and total testosterone levels in Iranian women with polycystic ovary syndrome after 12 weeks of treatment.
September 2025 in “Cureus” In this case report, a male patient with hair loss showed unusually high testosterone levels without other symptoms or supplement use; follow-up testing revealed normal levels, showcasing the importance of considering testosterone-protein binding differences and using equilibrium dialysis for accurate assessment.
May 2023 in “Problems of Endocrinology” This study observed that "physiological" hyperandrogenism due to elevated total testosterone was associated with a 23.5% incidence of arterial hypertension, unlike hyperandrogenism due to elevated DHT levels.
March 2004 in “Journal of The American Academy of Dermatology” This study found that patients with systemic lupus erythematosus and diffuse hair loss showed non-scarring alopecia without inflammation and a decrease in total hair follicles.
September 2023 in “International journal of science and healthcare research” In this report, a preterm neonate was found to have total irreversible hair loss due to congenital atrichia, confirmed by a mutation in the human hairless gene on chromosome 8p22, illustrating this rare autosomal recessive disorder.
July 2023 in “Journal of the Mexican chemical society” This study found that Hibiscus rosa-sinensis dried leaves extract displayed the strongest pancreatic lipase inhibitory activity among 37 tested plant extracts, showing potential as an anti-obesity agent with effects comparable to the pharmaceutical drug orlistat in reducing plasma triacylglycerol levels in rats.
2 citations
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April 2023 in “Pharmaceuticals” This review discusses the controversial cardiovascular safety and efficacy of subcutaneous testosterone therapy in postmenopausal women, noting that its long-term use appears safe, but CV risk assessments remain disputed.
1 citations
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May 2021 in “Problemy e̊ndokrinologii” This study found that in men, elevated androgen levels can occur at any age, with older men potentially exhibiting increased total testosterone due to higher levels of SHBG, and younger men showing various clinical manifestations like acne and alopecia.
June 2022 in “Evidence-based complementary and alternative medicine” This study found that acupressure on specific points improved health-related quality of life and reduced total testosterone levels and clinical symptoms in patients with polycystic ovary syndrome compared to controls.
42 citations
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July 1982 in “PubMed” This study found that a low estrogen-containing oral contraceptive normalized hormone levels and improved symptoms in women with polycystic ovary disease, with minimal side effects reported.
5 citations
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November 2021 in “World Family Medicine Journal /Middle East Journal of Family Medicine” In this study, it was found that higher test anxiety negatively correlated with lower OSCE performance among medical students at Taif Medical College, with female students experiencing a greater impact than males.
April 2026 in “Ankara Üniversitesi Veteriner Fakültesi Dergisi” This study found that Mueller-Hinton Agar performed better than Dermasel Agar for antifungal susceptibility testing of feline dermatophytes, providing reliable susceptibility data for effective antifungal therapy.
March 2026 in “European Urology Focus” This study found that the 4Kscore model, when adjusted for kallikrein marker changes due to finasteride use, improved the prediction of high-grade prostate cancer compared to adjusted total PSA alone in men taking 5-α-reductase inhibitors.
October 2023 in “Arab Gulf journal of scientific research” This study found that adding Cinnamomum zeylanicum bark extract to a powder shampoo formulation significantly improved antioxidant activity without affecting its cleansing ability, although its clinical effectiveness remains to be tested.
May 2023 in “Sučasna pedìatrìâ. Ukraïna” In a clinical observation study, researchers documented a case of total alopecia in an 11-year-old child, highlighting a potential link to genetic conditions such as autoimmune polyendocrinopathy candidiasis-ectodermal dystrophy (APECED syndrome) requiring further genetic and serological testing to verify the diagnosis.
March 2021 in “CRC Press eBooks” This review discusses the importance of physical examinations in trichology, emphasizing their role in diagnosing conditions like alopecia and hair dystrophies, and reports no new clinical results.
June 2025 in “Journal of Applied Toxicology” In this study, finasteride reduced oxidative stress, apoptosis, and inflammation in liver, kidney, and testis tissues of diabetic rats while boosting antioxidants, indicating potential protective effects that require further human trials for clinical application.
64 citations
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August 1999 in “The American journal of medicine” This study found that while a transscrotal testosterone patch increases serum testosterone levels in hypogonadal men with AIDS and weight loss, it does not improve weight, body cell mass, or quality of life.
18 citations
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May 2014 in “Menopause” This study found that a 5-mg daily dose of transdermal testosterone cream in postmenopausal women restored testosterone levels to those typical of premenopausal women.
12 citations
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October 2018 in “Aging male/The aging male” This study found that prostate cancer aggressiveness in men with obesity is associated with changes in age, BMI, testosterone, and estradiol levels, and that adipocyte-secreted molecules increase cancer cell aggressiveness in vitro.
9 citations
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February 2022 in “Biomedicines” This study suggests that testosterone therapy in AFAB individuals may modify the methylation of the ESR2 promoter, with changes influenced by factors like total testosterone levels and age.
7 citations
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January 2014 in “Case reports in endocrinology” This case report describes a testosterone- and cortisol-secreting adrenocortical oncocytoma causing hirsutism in a 23-year-old woman, highlighting adrenal oncocytomas as an important consideration for differential diagnosis.
7 citations
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May 2012 in “International Journal of Andrology” This study found that an oral testosterone formulation normalized serum testosterone levels and significantly reduced SHBG in men with experimentally induced hypogonadism after nine days of treatment, suggesting potential efficacy for testosterone deficiency.
6 citations
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November 1997 in “International Journal of Dermatology” This study found that women with acne and oligomenorrhea have higher levels of biologically active testosterone compared to those with acne and normal menstrual cycles.
February 2026 in “Andrology” This study highlights the need for a comprehensive andrological assessment at diagnosis, including semen and hormonal analysis, to guide fertility preservation strategies, and found that post-orchidectomy semen samples showed improved DNA integrity for assisted reproductive technologies.
April 2025 in “Journal of Clinical Medicine” In this study, women with suspected PCOS who reduced their intake of sweets, fatty red meat, and alcohol for over 6 months showed significantly lower total testosterone levels compared to those who did not, highlighting the benefit of targeted dietary changes on hormonal profiles.
September 2023 in “Deleted Journal” This study observed that lifestyle modifications resulting in weight loss improved menstrual irregularity and hormonal balance among infertile obese women with polycystic ovary syndrome, although changes in total testosterone and estrone were not significant.