TLDR Androgen levels can increase at any age, affecting symptoms like acne, hair loss, and prostate size.
The study on hyperandrogenism in 100 men categorized them into four groups based on androgen levels, revealing that androgen levels could increase at any age. Older men showed higher total testosterone due to increased SHBG, while younger men with elevated DHT levels experienced androgenic alopecia and acne. Group 1 had higher prostate volume and age but fewer acne complaints, Group 2 had more acne but less alopecia, Group 3 exhibited severe hyperandrogenism symptoms, and Group 4 was characterized by alopecia. The study emphasized the need to assess SHBG and free testosterone for accurate diagnosis and treatment, noting limitations in sample representativeness and the indirect method for measuring free testosterone.
153 citations
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March 2017 in “Endocrine” Male pattern baldness involves genetics, hormones, and needs better treatments.
32 citations
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August 1999 in “Journal of Investigative Dermatology” Early onset hair loss linked to genetics and androgen levels.
September 2021 in “Conference Proceedings” Older men with high total testosterone might not show symptoms, while younger men with hyperandrogenism may experience hair loss or acne.
22 citations
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May 2006 in “Experimental and Clinical Endocrinology & Diabetes” Calculated testosterone values are reliable for assessing hyperandrogenemia in women, making direct measurement unnecessary.
11 citations
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September 1990 in “Clinical Endocrinology” Girls with prepubertal simple hypertrichosis have higher dihydrotestosterone (DHT) levels.
32 citations
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January 1990 in “Clinical Endocrinology” Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
135 citations
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March 1984 in “Fertility and sterility” Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.
