Normalization of Testosterone Levels Using a Low Estrogen-Containing Oral Contraceptive in Women With Polycystic Ovary Syndrome

July 1982 in “ PubMed ”

Shailaja C. Raj, Madhwa H.G. Raj, Luther M. Talbert, Carol S. Sloan, Brona Hicks

testosterone low estrogen-containing oral contraceptive Loestrin polycystic ovary syndrome PCOS luteinizing hormone testosterone binding globulin unbound testosterone hair growth complexion birth control pill oral contraceptive hormone therapy

TLDR Loestrin effectively normalizes testosterone levels and improves PCOS symptoms with minimal side effects.

The study investigated the effects of a low estrogen-containing oral contraceptive, Loestrin, on 25 women with polycystic ovary syndrome (PCOS). The treatment successfully normalized elevated luteinizing hormone and testosterone levels, both total and unbound, while increasing testosterone binding globulin levels. Unbound testosterone levels began to decline within a week and normalized by 12 to 16 weeks. Additionally, participants experienced reduced hair growth and improved complexion within the same timeframe. The side effects of the treatment were minimal, suggesting that Loestrin was an effective and well-tolerated option for managing symptoms of PCOS.

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research Hair Growth and Androgen Responses in Hirsute Women Treated with Continuous Cyproterone Acetate and Cyclical Ethinyl Estradiol

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research Normalization of Testosterone Levels Using a Low Estrogen-Containing Oral Contraceptive in Women With Polycystic Ovary Syndrome

42 citations , July 1982 in “PubMed”

Loestrin effectively normalizes testosterone levels and improves PCOS symptoms with minimal side effects.