Testosterone- and Cortisol-Secreting Adrenocortical Oncocytoma: An Unusual Cause of Hirsutism

    January 2014 in “ Case reports in endocrinology ”
    Serap Baydur Şahin, Ahmet Fikret Yücel, Recep Bedir, Sabri Oğullar, Teslime Ayaz, Ekrem Algün
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    TLDR A woman's excessive hair growth was caused by a rare benign tumor in her adrenal gland, which was successfully removed.
    In 2014, a case report described a 23-year-old female with hirsutism due to a rare testosterone- and cortisol-secreting adrenocortical oncocytoma in her left adrenal gland. The patient had abnormal hormone levels, with total testosterone at 4.2 ng/mL, free testosterone over 100 pg/mL, and DHEAS at 574 µg/dL. An MRI revealed a 27 × 25 mm mass, which was removed via laparoscopic left adrenalectomy and confirmed to be a benign oncocytoma. Her hormone levels normalized post-surgery, confirming the tumor as the cause of her hirsutism. This case was the second reported instance of its kind, highlighting the need to consider adrenal oncocytomas when diagnosing hirsutism.
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