2 citations
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August 2021 in “Journal of pharmaceutical research international” This study concluded that fenugreek seed extract loaded solid lipid nanoparticles demonstrated enhanced skin retention and extended release, suggesting potential as a future alternative treatment for alopecia.
2 citations
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November 2016 in “Journal of Pakistan Association of Dermatologists” In this study, tacrolimus was as effective as clobetasol propionate in treating alopecia areata, suggesting it can serve as an alternative therapy option.
1 citations
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June 2024 in “BMC Oral Health” In this study, autologous platelet concentrates and topical steroids similarly reduced lesion size, Thongprasom scale, and pain in oral lichen planus patients, suggesting autologous platelet concentrates as a potential alternative treatment.
January 2026 in “European Journal of Therapeutics” In this study, researchers reported that applying topical 7.5% dapsone led to a significant decline in lichen planopilaris activity within a month and a sustained two-year remission in a patient intolerant to other treatments, suggesting dapsone as a promising alternative for managing this condition.
January 2026 in “Frontiers in Pharmacology” This review reports that topical minoxidil remains the primary treatment for androgenetic alopecia, while oral and sublingual forms offer alternative options, each with varying efficacy and side effects.
The researchers reported that a 4-aminopyridine-loaded gel promoted wound healing and hair follicle regeneration in burn models, suggesting it might be a promising alternative to existing burn treatments.
April 2025 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” This study found that topical minoxidil 5% remains the most common treatment for androgenic alopecia due to its high tolerability and patient satisfaction, but topical sildenafil 2% shows promise as an alternative, especially with positive hair thickness outcomes in certain areas.
March 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” In this study, eight Chinese patients with alopecia areata showed hair regrowth following combination therapy with a nonablative laser and topical minoxidil, with most patients not experiencing relapse after one year, suggesting a promising alternative treatment without significant side effects.
This case report discusses a patient with female androgenetic alopecia and chronic telogen effluvium, emphasizing the importance of follicular unclogging to enhance treatment effectiveness, combining deep cleaning, caffeine application, physical stimulation, and lifestyle changes as an individualized, effective alternative to oral medications.
April 2017 in “Journal of Investigative Dermatology” This study found that 10% carbamide peroxide significantly reduced acne lesions compared to a vehicle solution, suggesting it as an effective and safe alternative to benzoyl peroxide for treating mild to moderate acne.
46 citations
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March 2009 in “Die Pharmazie” This study describes the development of nanostructured lipid carriers for minoxidil as a potential alternative to conventional topical solutions, showing promise for use in topical formulations.
3 citations
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January 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study in mice found that topical pumpkin seed oil promoted hair growth and could be a promising alternative treatment for male pattern alopecia.
1 citations
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June 2020 in “Actas Dermo-Sifiliográficas” This review discusses emerging therapies for androgenetic alopecia, including topical finasteride, oral minoxidil, and intradermal dutasteride, and reports no clinical results; the authors highlight changes in treatment approaches.
April 2025 in “Acta Dermato Venereologica” This review evaluates 21 studies on minoxidil-induced allergic contact dermatitis, finding that some patients with contact dermatitis symptoms like erythema and pruritus are sensitized to minoxidil or its vehicle components and should consider patch testing and alternative formulations for proper management.
April 2023 in “UNESP Institutional Repository (São Paulo State University)” In this study, oral minoxidil at 5 mg/day improved hair density comparably to topical minoxidil 5% in men with androgenetic alopecia over 24 weeks, offering a viable alternative for those intolerant to topical application.
January 2025 in “Letters in Drug Design & Discovery” This study found that ozonated olive oil exhibited antifungal activity against Trichophyton mentagrophytes, comparable to the standard antifungal terbinafine, in an in vivo rat study, suggesting it may serve as an alternative treatment for dermatophytosis.
19 citations
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November 2017 in “Journal of Pharmaceutical Sciences” This research investigated aqueous alginate-based hydrogels for delivering minoxidil and reported that using hydroxypropyl-β-cyclodextrin (HP-β-CD) with molar substitution 0.65 significantly enhanced minoxidil's solubility and skin permeability without damaging the epidermis, suggesting potential as an alternative to commercial minoxidil solutions.
2 citations
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November 2023 in “Bioactive materials” The researchers reported that a newly developed ionic liquid-based microemulsion significantly improved the local delivery of copper peptides in mice, enhancing hair growth-related factor activation while offering a safer, non-invasive alternative to existing treatments for hair loss.
June 2025 in “Journal of the Faculty of Medicine Baghdad” This study found that Syzygium aromaticum oil may improve the anagen/telogen ratio in testosterone-induced alopecia in mice, indicating potential as an alternative treatment to minoxidil for androgenic alopecia.
March 2026 in “INDIAN DRUGS” In this study, an antioxidant-rich herbal hair mask with flaxseed and rice water was developed and showed 72% DPPH radical scavenging activity, stable physical parameters, and effective spreadability and foamability, suggesting it may be a cost-effective, environmentally-friendly alternative to artificial hair products.
22 citations
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March 2018 in “American Journal of Clinical Dermatology” New acne treatments show promise as alternatives to traditional therapies.
This article introduces REVVup Hair Therapy as an alternative to surgery for early-stage hair loss but reports no new clinical findings.
59 citations
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July 2020 in “Journal of The American Academy of Dermatology” This study concluded that oral minoxidil is an effective and well-tolerated alternative to topical minoxidil for healthy patients struggling with application-related compliance issues.
34 citations
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November 2023 in “Applied Materials Today” This review discusses the potential of topical nanoemulsions to transform skin cancer treatment by improving drug delivery and minimizing side effects, highlighting their advantages like enhanced skin permeation and controlled release, despite existing challenges.
24 citations
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January 2014 in “PubMed” This case report suggests that topical imiquimod cream may be an effective alternative treatment for generalized discoid lupus erythematosus without systemic involvement.
8 citations
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January 2020 in “Skin Pharmacology and Physiology” This article discusses the potential for topical caffeine as a natural alternative for treating androgenetic alopecia due to its ability to penetrate skin, but it reports no new clinical findings.
2 citations
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September 2014 in “PubMed” This review discusses low-level laser or light devices as an alternative treatment for androgenetic alopecia and highlights the need for further research to compare their efficacy with existing therapies.
1 citations
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July 2025 in “Journal of Cosmetic Dermatology” This case report suggests that exosome therapy may offer a promising alternative treatment for lichen planopilaris, showing potential benefits in hair regrowth, reduced inflammation, and improved scalp condition, but further studies are needed to confirm long-term efficacy and safety.
February 2026 in “Cureus” This case report suggests that crisaborole may be an effective alternative treatment for alopecia areata in pediatric patients, showing significant hair regrowth after two weeks in a 10-year-old girl.
This article provides an overview of current treatments and alternative formulations for androgenic alopecia but reports no new clinical results.