Comparative Study of Topical Sildenafil 2% and Topical Minoxidil 5% for Male Androgenic Alopecia Treatment
TLDR Minoxidil is the most common treatment for male hair loss, but sildenafil shows promise as an alternative.
This study compared the efficacy of topical sildenafil 2% and topical minoxidil 5% in treating male androgenic alopecia (AGA) in 50 patients. Over six months, Group A used sildenafil and Group B used minoxidil. Results showed that minoxidil had a strong positive association with age and vertex hair thickness, while sildenafil showed significant positive associations with VH responses at the frontal region and patient satisfaction. Age and AGA duration negatively affected VH activity in the vertex region and frontal area hair thickness, but positively correlated with hair density in both regions. The study concluded that while minoxidil remains the most common treatment due to its tolerability and satisfaction, sildenafil presents a promising alternative.
