Successful Treatment of Generalized Discoid Lupus Erythematosus With Imiquimod Cream 5%: A Case Report and Review of the Literature
January 2014
in “
PubMed
”
Studysummary This case report suggests that topical imiquimod cream may be an effective alternative treatment for generalized discoid lupus erythematosus without systemic involvement.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Discoid lupus erythematosus (DLE) is a chronic skin condition that can lead to scarring, hair loss, and pigmentary changes if not treated early. A case study of a 63-year-old man with generalized DLE, presenting with erythematous scaly patches on the face and other body parts, demonstrated successful treatment using imiquimod cream 5%. The cream was applied three times a week, every other week, resulting in almost complete recovery after 24 applications over two months. This case suggested that topical imiquimod could be an alternative treatment for generalized DLE.