TLDR Exosome treatment from stem cells improved hair regrowth and reduced scalp issues in a woman with lichen planopilaris.
A 35-year-old female with lichen planopilaris (LPP), a type of scarring alopecia, showed significant improvement in hair regrowth, decreased erythema, and reduced scalp scarring after receiving four sessions of topical exosome treatment derived from adipose stem cells. This case report highlights the potential of exosomes as a novel treatment for LPP, offering a steroid-sparing alternative with a favorable short-term side effect profile. Despite the promising results, the study acknowledges limitations such as the lack of long-term safety data, the single-case nature of the report, and the need for larger, controlled studies to confirm efficacy and determine optimal treatment protocols.
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March 2023 in “International Journal of Molecular Sciences” ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.
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March 2022 in “Frontiers in Cell and Developmental Biology” Colostrum-derived exosomes can promote hair growth and may be a promising treatment for hair loss.
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February 2022 in “Journal of cosmetic dermatology” Exosomes from fat-derived stem cells may help regrow hair.
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October 2022 in “Regenerative Therapy” New regenerative treatments for hair loss show promise but need more research for confirmation.
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May 2021 in “Dermatologic clinics” PRP and cell therapies may help with hair loss, but more research is needed.
December 2025 in “IP Indian Journal of Clinical and Experimental Dermatology” Androgenetic alopecia treatments are becoming more personalized and include new therapies like topical antiandrogens and regenerative strategies.
May 2024 in “Clinical Cosmetic and Investigational Dermatology” Manipulating cell cleanup processes could help treat hair loss.