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660-690 / 1000+ resultsresearch DGAT1 Modulates Hair Cycling and Is Essential for Retinoid Homeostasis in the Skin
This study found that the enzyme encoded by Dgat1 acts as a retinol acyltransferase in murine epidermis, protecting against retinoid toxicity and alopecia by preventing retinol accumulation.
research Vitamin A in Skin and Hair: An Update
This review discusses new research on the role of retinoids in skin and hair health and reports no clinical results.
research A natural deep eutectic solvent formulation promotes hair growth by enhancing the transdermal delivery and bioactivity of hydroxytyrosol
In this study, researchers developed a delivery system using a deep eutectic solvent to improve hydroxytyrosol absorption for hair regrowth, achieving over threefold greater skin penetration compared to aqueous solutions and demonstrating its effectiveness and biocompatibility in hair regrowth and ROS-scavenging tests.
research Collodion baby case series: the success of oral retinoic acid
This study reported dramatic improvements in five collodion baby patients with lamellar ichthyosis treated with oral retinoic acid, noting hair loss as the sole adverse effect, emphasizing the treatment's promising efficacy for physicians.
research Data for the article "Increased calcidiol level in redhaired people: Could redheadedness be an adaptation to temperate climate?"
This study found that redhaired individuals exhibit higher calcidiol levels compared to non-redhaired individuals, suggesting a possible evolutionary adaptation for vitamin D photosynthesis in low UV-B environments in Europe.
research Araliadiol Protects Human Keratinocytes From Oxidative Stress, DNA Damage, and Apoptosis via Activation of Antioxidant Signaling
This study reported that, in a laboratory setting, araliadiol derived from Centella asiatica activated antioxidant pathways, mitigating urban particulate matter-induced oxidative stress and skin damage.
research Novel Drugs Targeting Retinoic Acid Receptors
This article reviews different generations of synthetic retinoids for dermatological use, discussing their efficacy and significant side effects, but reports no new clinical results.
research Lentinula edodes (Shiitake) extract as a vitamin D receptor activator to enhance skin adaptogenic responses
This study suggests that a Lentinula edodes extract can improve skin barrier function, hydration, and sebum regulation, possibly by modulating vitamin D pathways, in individuals with oily and acne-prone skin.
research LC-ESI-QTOF-MS/MS characterization of phenolic compounds from Prosopis farcta (Banks & Sol.) J.F.Macbr. and their potential antioxidant activities
This study found that Prosopis farcta is a rich source of phenolic compounds with strong antioxidant activity, suggesting its potential for use in food, beverage, feed, and pharmaceutical applications.
research Corkscrew hairs
This case report describes a 22-year-old woman with systemic lupus erythematosus who developed scurvy due to low serum ascorbic acid, despite a diet of white meat and processed foods.
research The extract of Thujae occidentalis semen inhibited 5α-reductase and androchronogenetic alopecia of B6CBAF1/j hybrid mouse
This study showed that Thujae occidentalis semen extract inhibited 5alpha-reductase type 2 in laboratory tests and reduced androgen-related hair loss in animal models, suggesting potential use for male pattern baldness.
research [Current Topics on Vitamin D. The vitamin D functions in keratinocytes and its therapeutic applications].
This review discusses the role of vitamin D and its receptor in maintaining skin and hair follicle health, but it reports no new clinical findings.
research Efficacy of topical calcipotriol betamethasone dipropionate as a new adjuvant therapy to follicular unit extraction technique in treatment of stable vitiligo: clinical, dermoscopic and immunohistological study
This study found that combining follicular unit extraction with topical calcipotriol betamethasone dipropionate showed the best repigmentation results in treating stable nonsegmental vitiligo.
research The Molecular Mechanism Underlying the Proliferating and Preconditioning Effect of Vitamin C on Adipose-Derived Stem Cells
This study found that vitamin C increased the survival, proliferation, and hair-regenerative potential of adipose-derived stem cells through the MAPK pathway and enhanced hair growth in mice.
research Phenyl Propanoid 1’s-1′-Acetoxychavicol Acetate Protects Against Testosterone-Induced Alopecia by Inhibiting Nadph Oxidase
In this study, 1'-S-1'-acetoxychavicol acetate (ACA) from Alpinia galanga showed potential in suppressing testosterone-induced hair loss by inhibiting Nox isozymes in a mouse model of androgenetic alopecia.
research Topical Tacrolimus, Clobetasol, and Minoxidil (TCM) for Primary Cicatricial Alopecias: A Retrospective Analysis of Clinical Outcomes and Safety
This study reported that the combination of tacrolimus, clobetasol, and minoxidil improved hair measurements and stabilized inflammation in primary cicatricial alopecia patients, with most tolerating the treatment well.
research Aromatic plants as cosmeceuticals: benefits and applications for skin health
This review highlights the potential of aromatic plants as natural antioxidants in cosmeceuticals, which may combat skin aging and promote rejuvenation by counteracting oxidative stress, offering a natural alternative to synthetic products with benefits like photoprotection and anti-wrinkle effects.
research Cysteine Prevents the Reduction in Keratin Synthesis Induced by Iron Deficiency in Human Keratinocytes
This study found that cysteine supplementation significantly increases keratin expression in human keratinocytes, and counteracts the negative impact of iron deficiency on keratin production by enhancing iron availability for cellular processes.
research Interest of a vitamin and mineral supplement in the management of telogen effluvium: Clinical study on Brazilian women
A vitamin and mineral supplement significantly reduced hair shedding in Brazilian women with telogen effluvium.
research Tamarillo Polyphenols Encapsulated-Cubosome: Formation, Characterization, Stability during Digestion and Application in Yoghurt
This study found that encapsulating tamarillo polyphenols in cubosome nanoparticles protected them during digestion and enhanced the nutritional and antioxidant properties of yoghurt when used as a delivery system.
research [Genetic dissection of retinoic acid function in epidermis physiology].
This study demonstrated that mice lacking skin-specific RXRalpha expression developed hair follicle degeneration and alopecia, indicating the importance of RXRalpha/VDR heterodimers in maintaining hair follicle homeostasis.
research Sebaceous glands changes following topical application of citral
This study found that daily topical application of citral increased sebaceous gland lobules and cell hyperplasia in male rats after three months.
research Follicular Keratosis of the Chin Treated with 1.24R‐Dihydroxyvitamin D3 Ointment
In this case report, an ointment containing 1.24R-dihydroxyvitamin D3 was effective for treating follicular keratosis of the chin but did not provide lasting benefits after treatment ended.
research Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
This study found that astilbin downregulates effector CD4+ T cell activities through the CYP1B1/ROS/PPARγ pathway, suggesting its potential use in treating inflammation.
research Extensive review on the analytical methods for the estimation of Thuja occidentalis homeopathic mother tincture
This review presents analytical methods for estimating Thuja occidentalis in homeopathic mother tincture but reports no new clinical results, emphasizing its broad application in homeopathy.
research Retinoid Metabolism Is Altered in Human and Mouse Cicatricial Alopecia
This study found that C57BL/6 mice with a diet containing specific levels of vitamin A showed alterations in retinoid metabolism and increased frequency of cicatricial alopecias, suggesting dietary factors may play a role in this condition.
research Transcriptional activation of CCN1 and CCN2, targets of canonical Wnt signal, by ascorbic acid 2-phosphate in human dermal papilla cells
This review discusses the roles of epithelial-mesenchymal interactions and dermal papilla in hair follicle growth and cycling, but it reports no new clinical results.
research Khảo sát thành phần hóa học và điều kiện tách chiết Polyphenol, Flavonoid từ lá cây thạch vĩ (Pyrrosia lingua)
This study identified key natural compounds such as polyphenols and flavonoids in tongue fern and established optimal extraction conditions using methanol.
research A single topical application of calcipotriol (50μg/g) ointment has no acute effect on systemic calcium homeostasis in patients with chronic plaque psoriasis
This study found that a single topical application of calcipotriol ointment did not affect systemic calcium levels in patients with chronic plaque psoriasis.