10 citations
,
November 2024 in “Cureus” This systematic review identified several factors contributing to increased cardiovascular risk in women with polycystic ovary syndrome, including insulin resistance, obesity, inflammation markers, and microbiota alterations linked to elevated trimethylamine-N-oxide levels.
10 citations
,
October 2009 in “Clinical Therapeutics” This study found that the orally disintegrating tablet and standard tablet formulations of finasteride met bioequivalence criteria in fasting healthy adult male Han Chinese volunteers, although there was a significant difference in time to maximum concentration.
6 citations
,
February 2016 in “Journal of Microencapsulation” This study found that injectable finasteride microspheres provided a sustained drug release with a minimal initial burst in albino rabbits compared to oral suspension.
2 citations
,
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” This study provides the first draft of the male Asiatic lion's whole genome, revealing low genomic diversity and highlighting conservation concerns.
2 citations
,
September 2011 in “Chiang Mai Medical Journal - เชียงใหม่เวชสาร” This study demonstrated that the 5-mg generic finasteride tablet is bioequivalent to the original tablet when tested in healthy Thai male volunteers.
1 citations
,
August 2022 in “Frontiers in Physiology” This study suggests that finasteride may help alleviate high-fat diet-induced kidney damage in mice by reducing TMAO synthesis and regulating gut microbiota.
1 citations
,
January 2023 in “Metabolites” This review discusses the relationship between gut microbiota and polycystic ovarian syndrome (PCOS), including its potential mechanisms and the role of alterations in microbiome composition on PCOS pathophysiology.
This case report describes a 21-year-old woman with systemic lupus erythematosus who developed lupus nephritis in the context of thrombotic microangiopathy, including a rare presentation of cryoglobulin-like thrombi.
January 2012 in “Pharmacy Today” This study concluded that two formulations of finasteride were bioequivalent based on Cmax, AUC, and Tmax data from healthy volunteers.
January 2010 in “Chinese Journal of Hospital Pharmacy” This study found that finasteride test and reference tablets are bioequivalent in healthy male volunteers, with no significant differences in their pharmacokinetic parameters.
January 2005 in “Zhōnghuá yàoxué zázhì” This study concluded that two different finasteride tablet formulations are bioequivalent based on their pharmacokinetic profiles in a crossover trial with male subjects.
This study concluded that domestic and imported finasteride tablets are bioequivalent, showing no significant differences in pharmacokinetic parameters among healthy volunteers.
14 citations
,
January 2020 in “International Journal of Biological Sciences” This study found that ranitidine and finasteride may have cardiovascular and renal protective effects in mice by inhibiting TMAO synthesis and improving gut microbiota composition.
5 citations
,
February 2025 in “Pediatric Dermatology” In this study, ritlecitinib was generally well tolerated in pediatric alopecia areata patients aged 6 to <12 years, with no severe or serious adverse events reported, and the drug's pharmacokinetic parameters were successfully characterized.
January 2004 in “Chinese Journal of Pharmaceuticals” This study concluded that the test and reference finasteride tablets were bioequivalent in terms of pharmacokinetic parameters in healthy male volunteers.
21 citations
,
March 2021 in “Molecules” This study found that a new quercetin-loaded self-nanoemulsifying drug delivery system improved quercetin bioavailability by 149.8% compared to its suspension in rats.
1 citations
,
October 2023 in “Journal of personalized medicine” In this study, researchers investigated genetic variants in pharmacogenes affecting tadalafil and finasteride pharmacokinetics, finding fed volunteers had higher drug exposure than fasting individuals, but genetic variation did not significantly impact pharmacokinetics after correcting for multiple comparisons.
1 citations
,
January 2003 in “Zhongguo yaoke daxue xuebao” This study determined that finasteride test and reference tablets are bioequivalent in human participants, as no significant differences were found in their pharmacokinetic parameters.
1 citations
,
January 1995 in “Yakubutsu dōtai” This study found that the pharmacokinetics of a single oral dose of finasteride are similar between elderly and non-elderly adults, suggesting no significant impact of age.
January 2009 in “Chinese Journal of Drug Application and Monitoring” This study concluded that finasteride granules are bioequivalent to finasteride tablets based on pharmacokinetic evaluation in healthy male volunteers.
January 2007 in “Pharmaceutical Journal of Chinese People's Liberation Army” In this study, the researchers found that two formulations of finasteride tablets were bioequivalent in Chinese healthy male volunteers.
January 2003 in “The Chinese Journal of Clinical Pharmacology” In this study, the authors concluded that the tested and reference finasteride tablets showed bioequivalence in healthy male volunteers.
January 2003 in “The Chinese Journal of Clinical Pharmacology” In this study, an LC/MS/MS method was successfully developed to determine finasteride concentrations and study its pharmacokinetics in healthy male Chinese volunteers.
December 2022 in “Türk biyokimya dergisi” The conclusions are: fecal short-chain fatty acids may help prevent cancer, fiber intake can reduce obesity, weight loss is hard for obese people, low BMI cancer patients are more prone to chemotherapy side effects, intermittent fasting benefits gut health, cherry laurel has health benefits in rats, certain gene variations can increase stress in hair loss patients, fecal acids can affect blood sugar levels, cold agglutinin can affect blood test results in autoimmune patients, and people with Crohn's disease have higher levels of a certain chemical in their blood.
36 citations
,
January 2018 in “Clinical and Medical Reports” Rare earth elements are crucial in medical imaging and cancer treatment.
136 citations
,
April 2013 in “Clinical Cancer Research” The study found that IPI-926 was well tolerated up to 160 mg once daily for 28-day cycles and showed activity as a single-agent treatment in Hedgehog pathway inhibitor-naïve patients with basal cell carcinoma.
38 citations
,
February 2005 in “The journal of sexual medicine” This study found that a testosterone patch and gel showed bioequivalent testosterone levels in hypogonadal men, but the patch mimicked a natural circadian profile, while the gel resulted in higher dihydrotestosterone levels.
25 citations
,
February 1989 in “The Journal of Clinical Pharmacology” This document studied minoxidil in healthy volunteers. Minoxidil is quickly absorbed and eliminated from the body.
24 citations
,
February 2006 in “Chinese Medical Journal” This study found that dermal papilla cells cultured in vitro can promote hair follicle regeneration and maintain hair growth, with stronger ET-1 and SCF expression enhancing this regenerative ability.
7 citations
,
February 2016 in “Arab journal of urology” This study found that patients with androgenetic alopecia had a higher incidence of metabolic syndrome and benign prostatic hyperplasia compared to those without the condition.