Bioequivalence of Finasteride Tablets in Healthy Volunteers

The study aimed to evaluate the bioequivalence of finasteride tablets by analyzing their pharmacokinetics and relative bioavailability in 21 healthy male volunteers using a two-way crossover trial design. Plasma concentrations were measured after a single oral dose of 20 mg finasteride. The results showed that the pharmacokinetic parameters, including AUC0-tn, AUC0-∞, tmax, ρmax, and t1/2, were similar between the test and reference tablets. The study concluded that the two types of finasteride tablets were bioequivalent.