Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that combining adipose-derived mesenchymal stromal cells with meglumine antimoniate reduced lesion size and parasite load in mice with leishmaniasis, suggesting potential for improved treatment.

This study demonstrated that intraoperative bioprinting using a bioink with human adipose-derived extracellular matrix and stem cells achieved successful reconstruction of full-thickness craniomaxillofacial skin defects in rats, promoting wound closure, adipogenesis, and hair follicle-like structure formation within two weeks.

This review discusses scaffold materials and properties used in epidermal tissue engineering to promote skin regeneration and reports no new research findings.

This study concluded that mesenchymal stem cells from adipose tissue harvested using laser-assisted liposuction with selective photo-stimulation are as effective and low-risk for cell therapy as those obtained through conventional liposuction, based on their differentiation potential, cellular proliferation, and cytokine expression.

This review summarizes the recent advances in molecular mechanisms influencing tissue sensitivity to glucocorticoids, emphasizing novel mutations and new information on the glucocorticoid receptor's circadian rhythm and ligand-induced repression, but reports no new results.

This study demonstrates that bioequivalence for proposed 50-mg ritlecitinib capsules versus clinical 100-mg capsules can be supported using a PBPK model-based biowaiver, achieving over 90% probability of success.

In this study of duku trees along the Batanghari River in Indonesia, researchers identified traits in mother trees that may help select for resistance to stem canker disease.

This study demonstrated that CD19-CAR T cell therapy may promote structural regeneration in the skin of systemic sclerosis patients, as evidenced by histological improvements and fibroblast population changes, suggesting its potential for tissue remodeling in fibrotic diseases.

This review discusses the isolation, characterization, and potential clinical applications of tissue-derived extracellular vesicles in cancer diagnosis, prognosis, and treatment, noting their significance but highlighting the risks and need for appropriate protocols.

This review discusses the roles of dermal white adipose tissue (dWAT) as an insulator, antibiotic, and regenerative tissue, highlighting its importance in systemic metabolism and immune function, but reports no new clinical results.

In this study of patients with Androgenic Alopecia, micro-grafts containing HD-AFSCs resulted in significantly improved hair density and follicle count over 11 months compared to a saline solution, suggesting a potential alternative therapy for hair regrowth.

In this study, adipose-derived stem cells from superficial adipose tissue showed higher regenerative potential, and more macrophages were found in superficial than deep adipose tissue, potentially influenced by skin microbiota.

This study found that "micro skin tissue columns" improved wound healing by enhancing re-epithelialization, collagen deposition, dermal remodeling, and reducing inflammation without causing long-term donor site morbidity.

In this study, researchers observed that in a limb ischemia model, vascular transplants preserved for 3 days had better recovery from ischemia-reperfusion injury compared to those preserved for 7 days, with less tissue edema and necrosis.

This study reports that despite advancements in tissue engineering and biomaterials, translating laboratory findings into effective clinical treatments for urethral reconstruction remains inadequate due to lack of standardization and short clinical trial follow-ups.

This paper discusses the variability in COVID-19 susceptibility and severity, emphasizing factors like biological differences and suggesting potential precision medicine approaches, but it reports no new clinical results.

This review discusses the role of fibroblast heterogeneity in kidney pathology, particularly their contribution to tertiary lymphoid tissue formation, and reports no new results.

This study found that canine adipose-derived mesenchymal stem cell-derived dermal papilla-like tissues promoted new hair follicle formation and increased vascularization in mice, suggesting potential for hair regeneration.

This narrative review explores the potential influence of brown adipose tissue on polycystic ovary syndrome and reports no new experimental findings.

The study suggests that variability in platelet-derived growth factors in PRP is influenced by both patient-to-patient differences and the devices used for PRP preparation, contributing to inconsistent clinical outcomes in hair loss treatments.

This study found that dermal papilla-like tissues derived from canine adipose stem cells promoted new hair follicle formation and increased vascularization in athymic nude mice.

This dissertation investigated barriers to clinical translation of adipose-derived mesenchymal stem cell-based vascular grafts, highlighting issues with thrombosis in diabetic patients and proposing alternative cell sources to improve applicability.

This case study detailed a rare instance of Penile Thread Tourniquet Syndrome in a 10-year-old boy, where a thread caused localized infection and edema without urethral damage, ultimately resulting in a favorable outcome through surgical and conservative management.

This article highlights the versatility and potential of alginate and its derivatives in tissue engineering applications, discussing their properties, modification techniques, and various uses in enhancing tissue healing, bone regeneration, and cell growth.

This study, using multimodal profiling in mice, found that various tissues contain unique γδ T cell subsets adapted to their environment, revealing their functional diversity, lineage relationships, and similarities to CD8+ tissue-resident memory T cells.

This review discusses various approaches to treating alopecia, including drug therapy and hair transplantation, but reports no new research findings; the authors highlight the need for novel techniques like cell culturing.

This study found that synthetic melanin particles applied topically in mouse injury models improved wound healing, showing potential as a therapy for accelerated healing, including in human skin explants.

This review summarizes that polyesters hold promise for vascular tissue engineering due to their mechanical properties and biodegradability, but optimizing their use in repairing damaged blood vessels remains challenging due to the complexity of vascular tissues.

This article reviews the role of keratins in epithelial function and structure, discussing their involvement in growth control, organelle functions, and pathomechanisms of disorders, but reports no new clinical results.

This study suggests that nerve growth factor may support hair follicle growth in Liaoning cashmere goats through pathways involving its receptor, TrkA, particularly during the anagen phase.