71 citations
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August 2019 in “The journal of sexual medicine” In this study, transgender adolescents treated with testosterone for a median of 12 months experienced effective virilization, including voice deepening and increased hair growth, but also showed decreased HDL cholesterol and BMD z-scores, and increased hematocrit, with no short-term safety issues reported.
43 citations
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August 2014 in “Dermatologic Therapy” This study confirmed that a sulfotransferase enzyme test can effectively rule out 95.9% of nonresponders to 5% topical minoxidil for treating androgenetic alopecia.
36 citations
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December 2016 in “Journal of The American Academy of Dermatology” In this study, researchers evaluated the hair pull test and found that normal values should be reduced to two hairs or fewer, with no significant impact from hair washing, brushing, or lifestyle factors such as hair texture and medication use.
31 citations
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January 2017 in “Advances in Experimental Medicine and Biology” This review discusses the negative health impacts of testosterone deficiency and the potential adverse effects of 5α-reductase inhibitors, emphasizing the need for patient-physician discussions regarding these treatments.
14 citations
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December 1998 in “The Journal of Clinical Endocrinology and Metabolism” This study found that MENT is 10 times more potent than testosterone in suppressing gonadotropins and contributing to anabolism in monkeys, with a potentially wider therapeutic index for human androgen replacement and male contraception.
8 citations
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July 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” This study suggests that in gilthead seabream, DHT is involved in the onset of the meiotic phase of spermatogenesis and influences serum levels of E2 through regulation of aromatase activity.
8 citations
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February 2014 in “General and Comparative Endocrinology” In this study, exposure to the drug finasteride in Silurana tropicalis significantly increased testosterone levels in liver and testis tissues and altered gene expression related to male reproduction and oxidative stress.
8 citations
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February 2009 in “Current Women's Health Reviews” This review discusses the impact of testosterone therapy on postmenopausal women's sexual function and well-being but notes a lack of long-term safety studies and debates on defining androgen insufficiency.
8 citations
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August 2007 in “Histopathology” This article discusses the kinetic and topographical heterogeneity in follicular thyroid neoplasms and reports no new research findings; the authors emphasize understanding diverse growth patterns.
4 citations
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December 2025 in “Frontiers in Immunology” This systematic review of Mendelian randomization studies reports that autoimmune thyroid disease is associated with increased risk for numerous health conditions, including coronary atherosclerosis and rheumatoid arthritis, while decreasing risks for others, such as lung cancer.
3 citations
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February 2025 in “Endocrine” This study emphasizes the necessity of confirming elevated testosterone levels detected by immunoassay with liquid chromatography-tandem mass spectroscopy before pursuing more complex diagnostic evaluations.
3 citations
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February 2017 in “Archives of Medical Science” This study found that finasteride treatment in male rats may lead to changes in connexin 43 expression in the testes of their offspring, potentially affecting spermatogenesis.
2 citations
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January 2018 in “Biology and medicine” In this study, researchers observed that a significant number of women in Eket, Nigeria, have low testosterone levels, while a subset with high free testosterone may have polycystic ovary syndrome.
1 citations
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January 2018 in “Journal of Gynecologic Surgery” This article reports two cases where ovarian hyperthecosis caused hyperandrogenism in postmenopausal women, confirmed by imaging and resolved after bilateral oophorectomy.
1 citations
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January 2008 in “Proceedings of the 9th World Rabbit Congress, Verona, Italy, 10-13 June 2008” This study found that androgenic hormone levels did not explain growth differences between furless and furred male rabbits, despite a potential growth advantage in furless rabbits.
1 citations
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June 2024 in “Revista Colombiana de Endocrinología Diabetes & Metabolismo” This review concluded that for women, the benefits of testosterone implants are outweighed by risks, with possible higher rates of irreversible adverse effects than previously reported.
January 2026 in “E3S Web of Conferences” This study found that silver nanoparticles synthesized using Mitracarpus scaber extract showed potential hepatoprotective and anti-hyperplastic effects in rats, suggesting novel therapeutic strategies for managing liver injury and benign prostatic hyperplasia.
September 2025 in “Cureus” In this case report, a male patient with hair loss showed unusually high testosterone levels without other symptoms or supplement use; follow-up testing revealed normal levels, showcasing the importance of considering testosterone-protein binding differences and using equilibrium dialysis for accurate assessment.
In this systematic review, researchers observed that Toxoplasma gondii infection is associated with alterations in testosterone levels, generally increasing in humans but showing mixed effects in animals, highlighting a complex relationship that warrants further investigation.
March 2024 in “Journal of Applied and Natural Science” This study found that administering an alcoholic extract of Mentha spicata leaves significantly reduced testosterone levels and aggressive behavior in female rats with elevated testosterone, suggesting its potential protective role against such symptoms.
May 2023 in “International journal of pharmaceutical sciences and medicine” This study found that Helianthus annuus oil promoted hair growth in a testosterone-induced alopecia mouse model, with higher hair density observed compared to untreated mice, though it was less effective than the standard minoxidil treatment.
April 2020 in “Journal of the Endocrine Society” This case report highlights Leydig cell hyperplasia as a rare cause of increased testosterone and postmenopausal hirsutism, resolved after bilateral salpingo-oophorectomy in a 64-year-old woman.
October 2018 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that in women with PCOS in Port Harcourt, Nigeria, glucose homeostatic disorders were common, particularly among those with higher testosterone levels, suggesting the need for glucose disorder screening in this population.
June 2026 in “International Journal of Homoeopathic Sciences” In this case report, the researchers observed that a woman with longstanding Alopecia Universalis, who had not responded to various treatments, experienced hair regrowth and improved quality of life after two years of individualized homeopathic treatment centered around Natrum Muriaticum.
June 2021 in “Archives of Advances in Biosciences” This study suggests that finasteride at doses of 5 mg/kg BW or higher may adversely affect spermatogenesis and male fertility in NMRI mice.
8 citations
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January 2009 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This study reports a novel TRbeta gene mutation associated with resistance to thyroid hormone syndrome, which may contribute to various forms of alopecia in the affected family members.
24 citations
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October 1995 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that the LH response to nafarelin effectively distinguished gonadotropin deficiency from constitutional delay of puberty, performing comparably to the sleep test and offering certain advantages.
December 2025 in “International Journal of Medicine and Public Health” In this study, researchers found that overt hyperthyroidism was the most prevalent thyroid disorder among patients, especially in women, and it was characterized by classic symptoms like high pulse rate and weight loss, highlighting the importance of early identification and management to prevent complications.
53 citations
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February 2022 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This review discusses the use of antimüllerian hormone as a marker of ovarian reserve in infertility diagnosis and treatment, noting it reflects oocyte quantity but not health or pregnancy likelihood.
53 citations
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May 2010 in “Dermatologic Surgery” This article appears to be a table of contents or navigation page for a journal, not presenting any new findings or research results.