research 69-Year-Old Man With Nasal Congestion and Pre-Syncope
A 69-year-old man with sinus infection and fainting spells was diagnosed with a rare kidney disease, treated with steroids and a specific drug, which improved his condition.
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research Alopecia Universalis Associated with Ulcerative Colitis and the Role of Azathioprine
A man with complete hair loss and ulcerative colitis regrew hair after treatment with azathioprine.
research Impact of Constant Light Exposure During Pregnancy on Skin of Neonatal New Zealand Rabbits: Structural and Ultrastructural Study
Constant light exposure during pregnancy changes newborn rabbits' skin, affecting hair follicles, skin thickness, and pigment cells.
research Hair Loss Associated with Sertraline: Two Case Reports and Review
Sertraline, an antidepressant, may rarely cause hair loss.
research Short-Term Clinical Assessment of Treating Female Androgenic Alopecia with Autologous Stem Cells Derived from Human Hair Follicles
Using stem cells from hair follicles to treat female hair loss is safe and effective after six months.
research The Role of Micronutrients in Young Men Presenting with Hair Loss
Many young men with hair loss have low levels of vitamin D and B12.
research Hair Loss Associated with Sertraline: Two Case Reports and Review
Sertraline, an antidepressant, may cause hair loss in rare cases.
research Two Mechanisms Regulate Keratin K15 Expression in Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signaling
Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
research Acute Telogen Effluvium: A Post-Covid-19 Sequela
COVID-19 infection may cause hair loss.
research Case Report: Pemphigus Vulgaris in an Adolescent
An 18-year-old girl with pemphigus vulgaris needed strong medication and careful treatment due to ineffective initial therapies and side effects.
research Implication of Human Bacterial Gut Microbiota on Immune-Mediated and Autoimmune Dermatological Diseases and Their Comorbidities: A Narrative Review
An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.
research Thyroid Receptor Agonists for the Treatment of Androgenetic Alopecia
Thyroid receptor agonists may treat male pattern baldness without harmful side effects.
research Thyroid Receptor β: A Promising Target for Developing Novel Anti-Androgenetic Alopecia Drugs
Thyroid receptor β can help develop new drugs to treat hair loss.
research A Novel Missense Mutation Affecting the Human Hairless Thyroid Receptor Interacting Domain 2 Causes Congenital Atrichia
A specific gene mutation causes congenital hair loss.
research Non-Canonical Dimerization of the Androgen Receptor and Other Nuclear Receptors: Implications for Human Disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research Thyroid Hormones and Androgens Differentially Regulate Gene Expression in Testes and Ovaries of Sexually Mature Silurana Tropicalis
Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
research Vitamin D Receptor-Mediated Control of Soggy, Wise, and Hairless Gene Expression in Keratinocytes
Vitamin D receptor helps control hair growth genes in skin cells.
research Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An In Silico and In Vitro Study
Five preservatives may disrupt hormone function and need more health and environmental risk assessment.
research Fadrozole And Finasteride Exposures Modulate Sex Steroid- And Thyroid Hormone-Related Gene Expression In Silurana (Xenopus) Tropicalis Early Larval Development
Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
research A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity
A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.
research Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching Is an Integrated Measure of Receptor Function
Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.
research The Androgen Receptor and Its Use in Biological Assays: Looking Toward Effect-Based Testing and Its Applications
Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
research Ligand-Independent Actions of Vitamin D Receptor
The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.
research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
research Development and Progression of Alopecia in the Vitamin D Receptor Null Mouse
Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.
research Molecular Genetics of Androgen Insensitivity
Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.
research Is the Comb Over Dying? A Mouse Model for Male Pattern Baldness (Androgenic Alopecia)
The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.
research Atrichia Caused by Mutations in the Vitamin D Receptor Gene Is a Phenocopy of Generalized Atrichia Caused by Mutations in the Hairless Gene
Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.
research Hairless and Wnt Signaling: Allies in Epithelial Stem Cell Differentiation
The HR protein's role as a repressor is essential for controlling hair growth.
research Topical L-Thyroxine: The Cinderella Among Hormones Waiting to Dance on the Floor of Dermatological Therapy?
Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.