Three Cases of Alopecia Following Clinical Islet Transplantation

The document described three cases of alopecia in female patients following clinical islet transplantation for type 1 diabetes, potentially linked to tacrolimus-based immunosuppressive therapy. Alopecia developed approximately 7 years post-transplant, with two patients also receiving thymoglobulin. The incidence of alopecia post-transplant was estimated at <2.5% over 5 years, higher than the <1% prevalence in pre-transplant candidates. Despite the small sample size, the study suggested a potential link between immunosuppressive therapy and alopecia, highlighting the need for further research and discussion of this risk with transplant candidates.