research New Populations with Increased Cardiovascular Risk: Cardiovascular Disease in Dermatological Conditions
Some skin conditions may increase the risk of heart disease, but are not yet included in cardiovascular prevention guidelines.
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research Hairless: A Nuclear Receptor Corepressor Essential for Skin Function
The Hairless gene is crucial for healthy skin and hair growth.
research Microbiome in the Hair Follicle of Androgenetic Alopecia Patients
Hair loss patients have different microbes in hair follicles, possibly affecting hair loss.
research Retinoids and Phototherapy for Psoriasis
Retinoids and narrowband UVB phototherapy are effective for treating psoriasis and can reduce treatment time when used together.
research Ziziphus Mauritiana: A Comprehensive Review on Ethnopharmacological, Phytochemical, and Pharmacological Properties
Indian jujube has many medicinal properties and can help treat ailments like diabetes, inflammation, and cancer.
research Th1 Chemokine CXCL10 and Alopecia Areata: A Possible Target for Treatment
Targeting CXCL10 may help treat alopecia areata.
research Alopecia Areata: A Tissue-Specific Autoimmune Disease of the Hair Follicle
Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.
research Alopecia Areata: Animal Models
Alopecia areata is influenced by genetics and immune system factors, and better understanding could improve treatments.
research Alopecia Areata: A Possible Extraintestinal Manifestation of Crohn's Disease
Alopecia Areata might be linked to Crohn's disease.
research Response to Ustekinumab in Three Pediatric Patients with Alopecia Areata
Ustekinumab helped three kids with alopecia areata regrow hair.
research An Update of the Pathogenesis of Frontal Fibrosing Alopecia: What Does the Current Evidence Tell Us?
The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.
research Alopecia Diffusa While Using Interleukin-17 Inhibitors Against Psoriasis Vulgaris
IL-17 inhibitors for psoriasis may cause unexpected hair loss.
research The Contributory Roles of Th17 Lymphocyte and Cytotoxic T Lymphocyte at the Hair Bulge Region and Hair Bulb Area in Chronic Alopecia Areata Patients
Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.
research Janus Kinase Inhibitors Versus Other Biological Treatments in Alopecia Areata
Janus kinase inhibitors show promise in treating alopecia areata but need more safety research.
research Advances in Molecular Pathogenesis of Hidradenitis Suppurativa: Dysregulated Keratins and ECM Signaling
Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.
research Clinical and Immunological Impact of Booster Immunization With Recombinant mRNA Vaccines for SARS-CoV-2 in Patients With Pemphigus and Bullous Pemphigoid
Booster shots of mRNA vaccines for COVID-19 increased protective antibodies without worsening autoimmune skin conditions in patients.
research Decreased IL-10 Producing Regulatory B Cells in Patients With Alopecia Areata
People with alopecia areata have fewer IL-10 producing immune cells, which might contribute to the condition.
research LB789 Novel IFNγ Aptamer TAGX-0003 Protected Hair Follicles from Immune Privilege Collapse and Reversed Alopecia Areata-Like Phenotype in Humanized Mouse Model
TAGX-0003 protected hair follicles and reversed alopecia areata in a mouse model.
research SnapshotDx Quiz: September 2016
Scalp psoriasis features reversible hair loss and specific immune activation, with no significant hair follicle damage.
research Detection of Subtypes of T Helper Cells and Their Cytokines in Peripheral Blood of Patients with Systemic Lupus Erythematosus and Their Clinical Significances
Higher levels of certain immune cells and proteins are linked to more severe lupus symptoms.
research Alopecia Areata: Probing the Deforestation
The document concludes that doctors should recognize congenital triangular alopecia to avoid unnecessary treatments, as it does not respond to steroids like alopecia areata does.
research Lichen Planopilaris Is Characterized By Immune Privilege Collapse Of The Hair Follicle's Epithelial Stem Cell Niche
The study on lichen planopilaris (LPP) involved 42 adult patients and demonstrated that the disease was characterized by the collapse of immune privilege in the hair follicle's epithelial stem cell niche, specifically in the bulge area. This collapse was marked by increased expression of MHC class I and II molecules and a reduction in TGFβ2 and CD200 expression, leading to a Th1-biased cytotoxic T cell response. The findings suggested that interferon-γ (IFNγ) played a significant role in this process, indicating that LPP might be an autoimmune disease. The study proposed that protecting or restoring immune privilege in the bulge could be a therapeutic strategy for managing this form of cicatricial alopecia.
research When the Skin Meets the Bowel: A Case Study
Ulcerative colitis can cause skin issues due to immune system problems.
research In This Issue
Genetically repaired stem cells may treat certain genetic diseases, Th17 cells are key in fighting systemic fungal infections, hair loss in AGA is due to progenitor cell loss, and α-synuclein transfer might contribute to Parkinson's disease progression.
research Frontal Fibrosing Alopecia Shows Robust T Helper 1 and Janus Kinase 3 Skewing
Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.
research A Case of Myasthenia Gravis Following Alopecia Areata
A man developed myasthenia gravis after alopecia areata, and treatment improved his symptoms and stopped hair loss.
research Trichoptilosis Developing After First Exposure to Hair Gels
Hair gels may cause split ends in children.
research Development of Squamous Cell Carcinoma from Erythroplasia of Queyrat Following Photodynamic Therapy
Photodynamic therapy may not work for erythroplasia of Queyrat and could lead to invasive squamous cell carcinoma.
research Epidemiology and Burden of Alopecia Areata: A Systematic Review
Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.
research CXCR3 Blockade Inhibits T Cell Migration Into the Skin and Prevents Development of Alopecia Areata
Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.