18 citations
,
January 2008 in “Journal of The American Academy of Dermatology” This study found that the proteins GDNF, NTN, GFRα-1, GFRα-2, and c-Ret are differentially expressed during various stages of the human hair follicle cycle, with potential implications for hair biology.
16 citations
,
January 2007 in “Dermatology” This review summarizes recent progress in human hair follicle bulge cell research, particularly the characterization and isolation of these stem cells, but reports no new experimental results.
15 citations
,
February 2015 in “Cell & tissue research/Cell and tissue research” This review examines the role of P-cadherin in skin and hair biology, emphasizing its importance in human hair growth, cycling, and pigmentation, and reports no new research findings.
13 citations
,
January 2020 in “Experimental Dermatology” This pilot clinical trial suggests that platelet-rich plasma (PRP) treatment may increase hair density in patients with androgenetic alopecia, though outcomes varied between patients.
13 citations
,
August 2018 in “Journal of Molecular and Cellular Cardiology” This study demonstrated that finasteride treatment reduced cardiac dysfunction and hypertrophic remodeling in mice after myocardial infarction, suggesting potential as a therapeutic strategy for heart failure.
12 citations
,
February 2025 in “Scientific Reports” This study found that extracellular vesicles derived from mesenchymal stem cells and umbilical cord blood plasma enhanced wound healing and reduced scar formation in mice, suggesting their potential as therapeutic agents for skin repair.
12 citations
,
July 2021 in “Scientific Reports” This study found that exogenous glutamic acid can promote hair growth and keratinocyte proliferation, suggesting a novel signalling pathway in the skin.
12 citations
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May 2017 in “Pharmacology & therapeutics” This review discusses the mechanisms underlying immune tolerance failure in alopecia areata and highlights potential therapeutic avenues for restoring hair growth and achieving sustained remission, but reports no new clinical results.
12 citations
,
May 2016 in “British Journal of Dermatology” This article reviews androgenetic alopecia and its underlying mechanisms, highlighting genetic and androgen factors in its onset, and does not report new research results.
12 citations
,
May 2015 in “Molecular Medicine Reports” This study demonstrated that troxerutin may protect human dermal papilla cells from H2O2-induced damage and suggests potential in treating alopecia by inhibiting ROS-mediated cellular damage.
12 citations
,
November 2014 in “PLOS Computational Biology” In this study, researchers found that synchronization between expanding epithelial cells and background mesenchymal cells in the mouse hair cycle may be maintained by inhibitory regulation, with potential mediators of this regulation identified.
11 citations
,
September 2014 in “International Journal of Molecular Sciences” This study found that mycophenolate may stabilize β-catenin and counteract interferon-γ-induced catagen changes in human dermal papilla cells, which could promote hair growth.
10 citations
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August 2020 in “Journal of Bioscience and Bioengineering” This study reports that using activated platelet-rich plasma releasate in the preparation of bioengineered hair follicle germs enhanced follicular gene expression and significantly improved hair regeneration in vitro.
10 citations
,
January 2020 in “Advances in Dermatology and Allergology” This study suggests that the gene rs27647 polymorphism may play a role in the pathogenesis of severe acne vulgaris in post-adolescent male patients.
10 citations
,
April 2019 in “Journal of Analytical Science and Technology” In this study, hydrolysates of lactic acid bacteria were found to enhance hair growth in C57BL/6 male mice more effectively than 5% minoxidil.
10 citations
,
January 2016 in “PLOS ONE” This study investigated protein expression changes during mouse hair follicle cycles and suggested their involvement in biological networks, potentially identifying targets for hair disease therapy.
10 citations
,
August 2014 in “PLoS ONE” This study suggests that mammalian hair follicles may serve as a viable and non-invasive system for diagnosing traumatic brain injury, reflecting similar molecular responses observed in other tissues.
10 citations
,
July 2013 in “British Journal of Dermatology” High MUC-18/MCAM levels in blood indicate a worse outlook for melanoma patients.
9 citations
,
June 2021 in “Nutrients” In this study, fisetin applied to the dorsal skin of mice activated hair follicle stem cells through exosome secretion from keratinocytes, promoting hair growth.
9 citations
,
January 2021 in “RSC Advances” Non-thermal plasma helps hair grow by improving the area around hair follicles.
9 citations
,
June 2020 in “BMC Molecular and Cell Biology” This study found that stress hormones, particularly CRF, can inhibit hair growth and induce hair loss by affecting human dermal papilla cells and hair follicles, suggesting a functional HPA axis in these cells.
9 citations
,
November 2018 in “Drug Discovery Today” This review discusses insights from scar-free animal models and cellular factors in skin regeneration, suggesting potential strategies for developing scar-free treatments in clinical and cosmetic practices, but reports no new clinical results.
9 citations
,
January 2017 in “Elsevier eBooks” This chapter discusses the skin stem cell niche as a complex ecosystem and highlights the diverse components and interactions that influence stem cell function, but it reports no new experimental results.
9 citations
,
May 2012 in “PLOS ONE” This study found that integrin-linked kinase is crucial for various epidermal functions, including differentiation and barrier formation, and also plays a previously unreported role in melanocyte development and function.
8 citations
,
July 2024 in “Scientific Reports” This study reported that administering salicylates to wounds in adult mice promoted wound healing patterns similar to embryonic wounds, enabling complete wound regeneration and reduced scarring by activating AMPK and subsequent signaling pathways.
8 citations
,
May 2024 in “PLoS Biology” This study on feather pattern formation in chicken skin found that inhibiting gap junctional intercellular communication can lead to the emergence of new feather buds in specific spatial patterns, suggesting that GJIC may facilitate Turing-type periodic patterning by propagating inhibitory signals over long distances.
8 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” This study reported that exogenous R-spondin-1 can restore hair follicle neogenesis in adult mouse cells, highlighting differences in gene expression and signaling pathways between fetal and adult dermal papilla cells.
7 citations
,
January 2021 in “Evidence-based complementary and alternative medicine” This study suggests that porphyra-334 may have antiaging properties, promoting collagen synthesis, improving periorbital wrinkles, and supporting hair follicle growth through gene regulation.
7 citations
,
December 2020 in “Pharmaceutics” In this study, a mixture of tocopherol acetate, L-menthol, and stevioside was more effective in promoting hair growth in mice compared to tocopherol acetate or L-menthol alone.
6 citations
,
September 2021 in “AESTHETIC OROFACIAL SCIENCE” This review discusses the cost-effectiveness and potential benefits of platelet-rich plasma for facial dermal rejuvenation but reports no new clinical results.