This review explores the mechanisms and clinical applications of thymosin β4, highlighting its potential in various medical fields, but it presents no new research findings.
This laboratory study observed that Prunus Tomentosa Thumb Total Flavone significantly promoted hair growth and follicle maturation in a C57BL 6 mouse model of hair loss.
August 2025 in “International Journal of Cancer” This study reported that postnatal environmental factors, such as childhood height and early hospitalization for immune-related diseases, were associated with an increased risk of testicular germ-cell tumor, with minimal observed variation between seminomas and non-seminomas.
4 citations
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October 2022 in “International Journal of Molecular Sciences” In this study, Thy-1 was observed to play a critical role in wound healing in mice, particularly influencing vascular dynamics and blood perfusion during the healing process.
5 citations
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May 2023 in “Microbial Cell Factories” This study found that a newly produced version of KGF-1 with 135 residues maintained biological activity and could serve as an alternative to the standard 140-residue KGF-1.
16 citations
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December 2019 in “Animals” In this study, cashmere goats engineered to overexpress the Tβ4 gene in hair follicles produced more cashmere, indicating that Tβ4 promotes secondary hair follicle development and enhances yield.
26 citations
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February 2021 in “FEBS Journal” This review discusses potential immune therapies targeting regulatory T cells for age-related diseases and emphasizes the need for further research to translate these therapies into clinical practice.
188 citations
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June 1998 in “Molecular cell” This study found that mimicking the XPD point mutation in mice resulted in trichothiodystrophy-like symptoms, supporting the role of basal transcription and DNA repair defects in the disease.
27 citations
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March 2019 in “PLoS ONE” This study suggests that Thyroxine (T4) may promote key features of human skin wound healing, such as re-epithelialization and angiogenesis, in an ex vivo model.
150 citations
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June 1999 in “Oncogene”
June 2024 in “Benha Journal of Applied Sciences” This study found that β1 integrin expression may serve as an indicator of androgenetic alopecia severity and could be involved in the disease's development.
January 2025 in “Open Veterinary Journal” This study investigated tissue healing in cats with auto skin grafts, finding that those treated with a combination of platelet-rich plasma and tilapia skin bio-dressings showed improved tissue structure, reduced collagen density, and more widespread caspase-3 expression compared to other treatments.
August 2009 in “Mechanisms of Development”
November 2022 in “Journal of Investigative Dermatology” This study observed that three-dimensional cultures of dermal papilla cells enhanced endothelial cell migration and angiogenesis in vitro, which may improve vascularization in tissue-engineered skin constructs.
5 citations
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November 2022 in “Journal of Ginseng Research/Journal of ginseng research” This study investigated the role of autophagy in human dermal papilla cells and found that inhibiting autophagy accelerates the catagen phase by reducing Wnt/β-catenin signaling. Furthermore, adding ginsenoside Re appears to restore autophagy, suggesting potential benefits for mitigating hair loss linked to autophagy inhibition.
94 citations
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March 1996 in “Journal of Investigative Dermatology”
5 citations
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January 2001 in “Hair transplant forum international” This review discusses the 1998 effort by 21 ISHRS hair restoration surgeons to standardize techniques for follicular unit transplantation and mini-micrografting, without reporting new clinical results.
This study found that intrathyroidal injection of autologous platelet-rich plasma improved thyroid function and symptoms in hypothyroidism patients, without adverse events over one year.
82 citations
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October 2019 in “Frontiers in Immunology” This review discusses the features of regulatory T cells and the modulation of Foxp3, emphasizing post-translational modifications' impact on Treg function but reports no new clinical results.
October 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” FGF9 from certain T cells helps create new hair follicles during wound healing, which could potentially be used for hair loss treatments.
5 citations
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May 2023 in “European Journal of Human Genetics” This study found that mutations in the TULP3 gene are associated with progressive degeneration of the liver, kidney, and heart in adults, highlighting the importance of early detection and management.
March 2025 in “European Journal of Medical Genetics” This case report suggests that tofacitinib may effectively manage symptoms of AGS7 in a patient with an IFIH1 mutation, though further studies are needed to confirm its long-term safety and efficacy.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a novel G207E STING mutation causing a distinct phenotype involving alopecia, photosensitivity, and thyroid dysfunction, and suggests that common polymorphisms in TMEM173 and IFIH1 may influence disease presentation.
1 citations
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January 2016 in “Dermatology Online Journal” This case report documents a rare instance of triangular temporal alopecia in an adult woman, emphasizing the importance of correct diagnosis to avoid unnecessary treatments, and reviews the literature on TTA.
9 citations
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March 2015 in “Journal of Microbiology and Biotechnology” This study found that ultra-high molecular weight poly-γ-glutamic acid promoted hair growth in telogenic C57BL/6 mice by inhibiting 5-alpha reductase activity and inducing the anagen phase.
December 2023 in “Journal of ethnopharmacology” This study found that tribuloside, a flavonoid from Tribulus terrestris L., enhances melanin production in human melanocytes, zebrafish, and human skin samples without causing toxicity, potentially through inhibiting PDE to increase cAMP levels and promote the melanin biosynthesis pathway.
5 citations
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May 2023 in “Frontiers in Cell and Developmental Biology” This study used single-cell techniques and lineage tracing to reveal that integrin α6 expression in neural crest cells can differentiate them into Schwann cells, melanocytes, and fibroblasts in skin, identifying integrin α6 as a potential marker for these derivatives.
May 2026 in “International Journal of Dermatology” This study found that serum 3α-androstanediol glucuronide levels were higher in Indian women with female pattern hair loss and correlated with the severity of the condition.
August 2025 in “Bioactive Materials” In a murine model of androgenetic alopecia, this study found that the newly designed IGF-1 biomimetic peptide Ac-GFFY-IGF led to faster and superior hair regrowth compared to minoxidil, suggesting potential for improved human therapies.