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The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Beard cells, unlike scalp cells, produce growth factors in response to testosterone, which may explain differences in hair growth.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Losing weight and taking birth control pills can greatly improve severe male hormone excess in women with PCOS.

Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.

Testosterone is made by Leydig cells, is active when not bound to proteins, and works by binding to receptors in muscles and other tissues.

New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.

The testes produce sperm and hormones essential for male development.

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

Compound 15a was effective in inhibiting 5α-reductase.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.

New compounds may soon be tested to treat excessive hair growth in women.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

PSA can help diagnose high androgen levels in women.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.